Benzofuran-based estrogen receptor α modulators as anti-cancer therapeutics : in silico and experimental studies
In the search for new estrogen receptor alpha (ERα) modulators, a trial molecular screening was conducted and 5,6-dihydroxybenzofuran was identified as a possible drug target for ERα. The target molecular modelling molecule 1 and a series of 5,6-dihydroxybenzofurans have been synthesized and evaluat...
Saved in:
Main Authors: | Leow, Min Li, Chin, Christina Hui Li, Yu, Peggy Shuang, Pasunooti, Kalyan Kumar, Tay, Raymond Xu Zhan, Zhang, Dawei, Yoon, Ho Sup, Liu, Xue-Wei |
---|---|
Other Authors: | School of Physical and Mathematical Sciences |
Format: | Article |
Language: | English |
Published: |
2013
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/99750 http://hdl.handle.net/10220/17385 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
Similar Items
-
Synthesis and biological studies of benzofuran-based estrogen receptor α modulators, pyridone alkaloids and zanamivir
by: Leow, Min Li
Published: (2014) -
Benzofuran-fused phosphole : synthesis, electronic, and electroluminescence properties
by: Chen, Hui, et al.
Published: (2013) -
Whole-genome cartography of estrogen receptor α binding sites
by: Lin, C.-Y., et al.
Published: (2015) -
Concise synthesis of α-substituted 2-benzofuranmethamines and other 2-subsituted benzofurans via α-substituted 2-benzofuranmethyl carbocation intermediates
by: Nikhom Wongsa, et al.
Published: (2018) -
Concise synthesis of α-substituted 2-benzofuranmethamines and other 2-subsituted benzofurans via α-substituted 2-benzofuranmethyl carbocation intermediates
by: Nikhom Wongsa, et al.
Published: (2018)