Salting effects on protein components in aqueous NaCl and urea solutions : toward understanding of urea-induced protein denaturation
The mechanism of urea-induced protein denaturation is explored through studying the salting effect of urea on 14 amino acid side chain analogues, and N-methylacetamide (NMA) which mimics the protein backbone. The solvation free energies of the 15 molecules were calculated in pure water, aqueous urea...
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Main Authors: | Mu, Yuguang, Li, Weifeng, Zhou, Ruhong |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2013
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/99763 http://hdl.handle.net/10220/17180 |
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Institution: | Nanyang Technological University |
Language: | English |
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