Development of safe and effective RSV vaccine by modified CD4 epitope in g protein core fragment (GcF)

10.1371/journal.pone.0094269

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Main Authors:	Cheon I.S., Shim B.-S., Park S.-M., Choi Y., Jang J.E., Jung D.I., Kim J.-O., Chang J., Yun C.-H., Song M.K.
Other Authors:	NUSHS PROJECT
Format:	Article
Published:	2019
Subjects:	alanine CD4 antigen guanine nucleotide binding protein guanine nucleotide binding protein core fragment immunoglobulin G respiratory syncytial virus vaccine unclassified drug epitope G glycoprotein, Respiratory syncytial virus virus fusion protein amino acid substitution animal cell animal experiment animal model article CD4+ T lymphocyte controlled study drug efficacy drug safety female immune response immunization immunoglobulin blood level mouse nonhuman Respiratory syncytial pneumovirus Respiratory syncytial pneumovirus A 2 Respiratory syncytial pneumovirus B respiratory syncytial virus infection vaccine production weight change weight reduction animal chemistry immunology safety Animals CD4-Positive T-Lymphocytes Epitopes, T-Lymphocyte Female Mice Respiratory Syncytial Virus Vaccines Safety Viral Fusion Proteins
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161417
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1614172024-11-10T01:11:32Z Development of safe and effective RSV vaccine by modified CD4 epitope in g protein core fragment (GcF) Cheon I.S. Shim B.-S. Park S.-M. Choi Y. Jang J.E. Jung D.I. Kim J.-O. Chang J. Yun C.-H. Song M.K. NUSHS PROJECT DUKE-NUS MEDICAL SCHOOL alanine CD4 antigen guanine nucleotide binding protein guanine nucleotide binding protein core fragment immunoglobulin G respiratory syncytial virus vaccine unclassified drug epitope G glycoprotein, Respiratory syncytial virus respiratory syncytial virus vaccine virus fusion protein amino acid substitution animal cell animal experiment animal model article CD4+ T lymphocyte controlled study drug efficacy drug safety female immune response immunization immunoglobulin blood level mouse nonhuman Respiratory syncytial pneumovirus Respiratory syncytial pneumovirus A 2 Respiratory syncytial pneumovirus B respiratory syncytial virus infection vaccine production weight change weight reduction animal chemistry immunology safety Animals CD4-Positive T-Lymphocytes Epitopes, T-Lymphocyte Female Mice Respiratory Syncytial Virus Vaccines Safety Viral Fusion Proteins 10.1371/journal.pone.0094269 PLoS ONE 9 4 e94269 2019-11-05T00:38:14Z 2019-11-05T00:38:14Z 2014 Article Cheon I.S., Shim B.-S., Park S.-M., Choi Y., Jang J.E., Jung D.I., Kim J.-O., Chang J., Yun C.-H., Song M.K. (2014). Development of safe and effective RSV vaccine by modified CD4 epitope in g protein core fragment (GcF). PLoS ONE 9 (4) : e94269. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0094269 1932-6203 https://scholarbank.nus.edu.sg/handle/10635/161417 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	alanine CD4 antigen guanine nucleotide binding protein guanine nucleotide binding protein core fragment immunoglobulin G respiratory syncytial virus vaccine unclassified drug epitope G glycoprotein, Respiratory syncytial virus respiratory syncytial virus vaccine virus fusion protein amino acid substitution animal cell animal experiment animal model article CD4+ T lymphocyte controlled study drug efficacy drug safety female immune response immunization immunoglobulin blood level mouse nonhuman Respiratory syncytial pneumovirus Respiratory syncytial pneumovirus A 2 Respiratory syncytial pneumovirus B respiratory syncytial virus infection vaccine production weight change weight reduction animal chemistry immunology safety Animals CD4-Positive T-Lymphocytes Epitopes, T-Lymphocyte Female Mice Respiratory Syncytial Virus Vaccines Safety Viral Fusion Proteins
spellingShingle	alanine CD4 antigen guanine nucleotide binding protein guanine nucleotide binding protein core fragment immunoglobulin G respiratory syncytial virus vaccine unclassified drug epitope G glycoprotein, Respiratory syncytial virus respiratory syncytial virus vaccine virus fusion protein amino acid substitution animal cell animal experiment animal model article CD4+ T lymphocyte controlled study drug efficacy drug safety female immune response immunization immunoglobulin blood level mouse nonhuman Respiratory syncytial pneumovirus Respiratory syncytial pneumovirus A 2 Respiratory syncytial pneumovirus B respiratory syncytial virus infection vaccine production weight change weight reduction animal chemistry immunology safety Animals CD4-Positive T-Lymphocytes Epitopes, T-Lymphocyte Female Mice Respiratory Syncytial Virus Vaccines Safety Viral Fusion Proteins Cheon I.S. Shim B.-S. Park S.-M. Choi Y. Jang J.E. Jung D.I. Kim J.-O. Chang J. Yun C.-H. Song M.K. Development of safe and effective RSV vaccine by modified CD4 epitope in g protein core fragment (GcF)
description	10.1371/journal.pone.0094269
author2	NUSHS PROJECT
author_facet	NUSHS PROJECT Cheon I.S. Shim B.-S. Park S.-M. Choi Y. Jang J.E. Jung D.I. Kim J.-O. Chang J. Yun C.-H. Song M.K.
format	Article
author	Cheon I.S. Shim B.-S. Park S.-M. Choi Y. Jang J.E. Jung D.I. Kim J.-O. Chang J. Yun C.-H. Song M.K.
author_sort	Cheon I.S.
title	Development of safe and effective RSV vaccine by modified CD4 epitope in g protein core fragment (GcF)
title_short	Development of safe and effective RSV vaccine by modified CD4 epitope in g protein core fragment (GcF)
title_full	Development of safe and effective RSV vaccine by modified CD4 epitope in g protein core fragment (GcF)
title_fullStr	Development of safe and effective RSV vaccine by modified CD4 epitope in g protein core fragment (GcF)
title_full_unstemmed	Development of safe and effective RSV vaccine by modified CD4 epitope in g protein core fragment (GcF)
title_sort	development of safe and effective rsv vaccine by modified cd4 epitope in g protein core fragment (gcf)
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161417
_version_	1821189011764412416

Development of safe and effective RSV vaccine by modified CD4 epitope in g protein core fragment (GcF)

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