Development of safe and effective RSV vaccine by modified CD4 epitope in g protein core fragment (GcF)

Development of safe and effective RSV vaccine by modified CD4 epitope in g protein core fragment (GcF)

10.1371/journal.pone.0094269

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Bibliographic Details
Main Authors:	Cheon I.S., Shim B.-S., Park S.-M., Choi Y., Jang J.E., Jung D.I., Kim J.-O., Chang J., Yun C.-H., Song M.K.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2019
Subjects:	alanine CD4 antigen guanine nucleotide binding protein guanine nucleotide binding protein core fragment immunoglobulin G respiratory syncytial virus vaccine unclassified drug epitope G glycoprotein, Respiratory syncytial virus virus fusion protein amino acid substitution animal cell animal experiment animal model article CD4+ T lymphocyte controlled study drug efficacy drug safety female immune response immunization immunoglobulin blood level mouse nonhuman Respiratory syncytial pneumovirus Respiratory syncytial pneumovirus A 2 Respiratory syncytial pneumovirus B respiratory syncytial virus infection vaccine production weight change weight reduction animal chemistry immunology safety Animals CD4-Positive T-Lymphocytes Epitopes, T-Lymphocyte Female Mice Respiratory Syncytial Virus Vaccines Safety Viral Fusion Proteins
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161417
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Institution:	National University of Singapore

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