TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter

TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter

10.1371/journal.ppat.1006681

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書目詳細資料
Main Authors:	Rajagopalan D., Pandey A.K., Xiuzhen M.C., Lee K.K., Hora S., Zhang Y., Chua B.H., Kwok H.S., Bhatia S.S., Deng L.W., Tenen D.G., Kappei D., Jha S.
其他作者:	MEDICINE
格式:	Article
出版:	Public Library of Science 2020
主題:	oncoprotein telomerase telomerase reverse transcriptase transactivator protein transactivator protein 60 transcription factor Sp1 unclassified drug histone acetyltransferase KAT5 protein, human Sp1 protein, human TERT protein, human tumor protein acetylation Article catalysis cell immortalization chromatin immunoprecipitation colony formation controlled study down regulation enzyme active site gene overexpression genetic transfection growth inhibition human human cell luciferase assay mass spectrometry molecular biology promoter region protein expression real time polymerase chain reaction RNA isolation site directed mutagenesis telomeric repeat amplification protocol transient transfection uterine cervix cancer virus infection Wart virus Western blotting biosynthesis DNA responsive element female gene expression regulation genetics HeLa cell line metabolism uterine cervix tumor Female Gene Expression Regulation, Enzymologic Gene Expression Regulation, Neoplastic HeLa Cells Histone Acetyltransferases Humans Neoplasm Proteins Response Elements Sp1 Transcription Factor Telomerase Uterine Cervical Neoplasms
在線閱讀:	https://scholarbank.nus.edu.sg/handle/10635/165368
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!

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