Elite Model for the Generation of Induced Pluripotent Cancer Cells (iPCs)

• Main Authors: Lai J., Kong C.M., Mahalingam D., Xie X., Wang X.
• Other Authors: MECHANOBIOLOGY INSTITUTE
• Format: Article
• Published: Public Library of Science 2020
• Subjects: cyclin dependent kinase inhibitor 2A; cyclin dependent kinase inhibitor 2B; DNA; protein p53; RNA; animal cell; animal experiment; animal model; article; cancer cell; CDKN2A gene; CDKN2B gene; cell heterogeneity; controlled study; elite model; fetus; gene deletion; gene expression; gene mutation; human; human cell; induced pluripotent cancer cell; microarray analysis; model; mouse; nonhuman; nuclear reprogramming; parsimony analysis; pluripotent stem cell; reverse transcription polymerase chain reaction; TP53 gene; Western blotting; Animals; Blotting, Western; Cell Line; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Gene Expression Regulation, Neoplastic; HeLa Cells; Humans; Induced Pluripotent Stem Cells; Mice; Mice, Nude; Mice, SCID; Models, Genetic; Molecular Sequence Data; Neoplasms, Experimental; Neoplastic Stem Cells; Nuclear Reprogramming; Pluripotent Stem Cells; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Transplantation, Heterologous; Tumor Suppressor Protein p53
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/166201
• Institution: National University of Singapore

10.1371/journal.pone.0056702