Reactive Metabolite-induced Protein Glutathionylation: A Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity

Reactive Metabolite-induced Protein Glutathionylation: A Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity

10.1074/mcp.RA118.000875

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Bibliographic Details
Main Authors:	Chan, James Chun Yip, Soh, Alex Cheow Khoon, Kioh, Dorinda Yan Qin, Li, Jianguo, Verma, Chandra, Koh, Siew Kwan, Beuerman, Roger Wilmer, Zhou, Lei, Chan, Eric Chun Yong
Other Authors:	BIOLOGY (NU)
Format:	Article
Language:	English
Published:	American Society for Biochemistry and Molecular Biology Inc. 2020
Subjects:	Science & Technology Life Sciences & Biomedicine Biochemical Research Methods Biochemistry & Molecular Biology Post-translational modifications Metabolomics Chemical biology Protein Modification Protein adducts Acetaminophen Drug-induced toxicity Hepatotoxicity Protein glutathionylation PARA-BENZOQUINONE IMINE S-GLUTATHIONYLATION IN-VIVO MITOCHONDRIAL RESPIRATION COVALENT BINDING OXIDATIVE STRESS REDOX REGULATION PLASMA-MEMBRANE OXIDANT STRESS LIVER
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/171313
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Institution:	National University of Singapore
Language:	English

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Summary:	10.1074/mcp.RA118.000875