Reactive Metabolite-induced Protein Glutathionylation: A Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity
10.1074/mcp.RA118.000875
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American Society for Biochemistry and Molecular Biology Inc.
2020
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sg-nus-scholar.10635-1713132024-04-05T09:01:41Z Reactive Metabolite-induced Protein Glutathionylation: A Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity Chan, James Chun Yip Soh, Alex Cheow Khoon Kioh, Dorinda Yan Qin Li, Jianguo Verma, Chandra Koh, Siew Kwan Beuerman, Roger Wilmer Zhou, Lei Chan, Eric Chun Yong BIOLOGY (NU) PHARMACY DUKE-NUS MEDICAL SCHOOL Science & Technology Life Sciences & Biomedicine Biochemical Research Methods Biochemistry & Molecular Biology Post-translational modifications Metabolomics Chemical biology Protein Modification Protein adducts Acetaminophen Drug-induced toxicity Hepatotoxicity Protein glutathionylation PARA-BENZOQUINONE IMINE S-GLUTATHIONYLATION IN-VIVO MITOCHONDRIAL RESPIRATION COVALENT BINDING OXIDATIVE STRESS REDOX REGULATION PLASMA-MEMBRANE OXIDANT STRESS LIVER 10.1074/mcp.RA118.000875 MOLECULAR & CELLULAR PROTEOMICS 17 10 2034-2050 2020-07-16T03:44:37Z 2020-07-16T03:44:37Z 2018-10-01 2020-07-15T08:56:35Z Article Chan, James Chun Yip, Soh, Alex Cheow Khoon, Kioh, Dorinda Yan Qin, Li, Jianguo, Verma, Chandra, Koh, Siew Kwan, Beuerman, Roger Wilmer, Zhou, Lei, Chan, Eric Chun Yong (2018-10-01). Reactive Metabolite-induced Protein Glutathionylation: A Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity. MOLECULAR & CELLULAR PROTEOMICS 17 (10) : 2034-2050. ScholarBank@NUS Repository. https://doi.org/10.1074/mcp.RA118.000875 15359476 15359484 https://scholarbank.nus.edu.sg/handle/10635/171313 en American Society for Biochemistry and Molecular Biology Inc. Elements |
| institution |
National University of Singapore |
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NUS Library |
| continent |
Asia |
| country |
Singapore Singapore |
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NUS Library |
| collection |
ScholarBank@NUS |
| language |
English |
| topic |
Science & Technology Life Sciences & Biomedicine Biochemical Research Methods Biochemistry & Molecular Biology Post-translational modifications Metabolomics Chemical biology Protein Modification Protein adducts Acetaminophen Drug-induced toxicity Hepatotoxicity Protein glutathionylation PARA-BENZOQUINONE IMINE S-GLUTATHIONYLATION IN-VIVO MITOCHONDRIAL RESPIRATION COVALENT BINDING OXIDATIVE STRESS REDOX REGULATION PLASMA-MEMBRANE OXIDANT STRESS LIVER |
| spellingShingle |
Science & Technology Life Sciences & Biomedicine Biochemical Research Methods Biochemistry & Molecular Biology Post-translational modifications Metabolomics Chemical biology Protein Modification Protein adducts Acetaminophen Drug-induced toxicity Hepatotoxicity Protein glutathionylation PARA-BENZOQUINONE IMINE S-GLUTATHIONYLATION IN-VIVO MITOCHONDRIAL RESPIRATION COVALENT BINDING OXIDATIVE STRESS REDOX REGULATION PLASMA-MEMBRANE OXIDANT STRESS LIVER Chan, James Chun Yip Soh, Alex Cheow Khoon Kioh, Dorinda Yan Qin Li, Jianguo Verma, Chandra Koh, Siew Kwan Beuerman, Roger Wilmer Zhou, Lei Chan, Eric Chun Yong Reactive Metabolite-induced Protein Glutathionylation: A Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity |
| description |
10.1074/mcp.RA118.000875 |
| author2 |
BIOLOGY (NU) |
| author_facet |
BIOLOGY (NU) Chan, James Chun Yip Soh, Alex Cheow Khoon Kioh, Dorinda Yan Qin Li, Jianguo Verma, Chandra Koh, Siew Kwan Beuerman, Roger Wilmer Zhou, Lei Chan, Eric Chun Yong |
| format |
Article |
| author |
Chan, James Chun Yip Soh, Alex Cheow Khoon Kioh, Dorinda Yan Qin Li, Jianguo Verma, Chandra Koh, Siew Kwan Beuerman, Roger Wilmer Zhou, Lei Chan, Eric Chun Yong |
| author_sort |
Chan, James Chun Yip |
| title |
Reactive Metabolite-induced Protein Glutathionylation: A Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity |
| title_short |
Reactive Metabolite-induced Protein Glutathionylation: A Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity |
| title_full |
Reactive Metabolite-induced Protein Glutathionylation: A Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity |
| title_fullStr |
Reactive Metabolite-induced Protein Glutathionylation: A Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity |
| title_full_unstemmed |
Reactive Metabolite-induced Protein Glutathionylation: A Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity |
| title_sort |
reactive metabolite-induced protein glutathionylation: a potentially novel mechanism underlying acetaminophen hepatotoxicity |
| publisher |
American Society for Biochemistry and Molecular Biology Inc. |
| publishDate |
2020 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/171313 |
| _version_ |
1800914115656417280 |