A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma

A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma

10.18632/oncotarget.14606

Saved in:
Bibliographic Details
Main Authors: Dai X., Wang L., Deivasigamni A., Looi C.Y., Karthikeyan C., Trivedi P., Chinnathambi A., Alharbi S.A., Arfuso F., Dharmarajan A., Goh B.C., Hui K.M., Kumar A.P., Mustafa M.R., Sethi G.
Other Authors: PHARMACY
Format: Article
Published: 2020
Subjects:
acetylcysteine
benzimidazole derivative
caspase 3
methyl 2 (5 fluoro 2 hydroxyphenyl) 1h benzo[d]imidazole 5 carboxylate
reactive oxygen metabolite
stress activated protein kinase
unclassified drug
animal experiment
animal model
animal tissue
antineoplastic activity
apoptosis
Article
cancer inhibition
cell invasion
cell migration
cell viability
controlled study
female
flow cytometry
human
human cell
liver cell carcinoma
mitochondrion
mouse
nonhuman
signal transduction
Western blotting
Online Access:https://scholarbank.nus.edu.sg/handle/10635/173807
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: National University of Singapore

Internet

https://scholarbank.nus.edu.sg/handle/10635/173807

Similar Items