Development of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic kras V12 expression in transgenic zebrafish

10.1038/srep19559

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Main Authors: Nguyen A.T., Koh V., Spitsbergen J.M., Gong Z.
Other Authors: BIOCHEMISTRY
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Published: Nature Publishing Group 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/175440
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spelling sg-nus-scholar.10635-1754402024-04-22T02:59:36Z Development of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic kras V12 expression in transgenic zebrafish Nguyen A.T. Koh V. Spitsbergen J.M. Gong Z. BIOCHEMISTRY BIOLOGICAL SCIENCES hybrid protein animal antibody specificity cell transformation disease model gene expression gene targeting gene vector genetics homologous recombination liver cell carcinoma liver tumor metabolism oncogene ras pathology signal transduction transgenic animal Wnt signaling pathway zebra fish Animals Animals, Genetically Modified Carcinoma, Hepatocellular Cell Transformation, Neoplastic Disease Models, Animal Gene Expression Gene Targeting Genes, ras Genetic Vectors Homologous Recombination Liver Neoplasms MAP Kinase Signaling System Organ Specificity Recombinant Fusion Proteins Wnt Signaling Pathway Zebrafish 10.1038/srep19559 Scientific Reports 6 19559 2020-09-10T01:41:22Z 2020-09-10T01:41:22Z 2016 Article Nguyen A.T., Koh V., Spitsbergen J.M., Gong Z. (2016). Development of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic kras V12 expression in transgenic zebrafish. Scientific Reports 6 : 19559. ScholarBank@NUS Repository. https://doi.org/10.1038/srep19559 20452322 https://scholarbank.nus.edu.sg/handle/10635/175440 Nature Publishing Group Unpaywall 20200831
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic hybrid protein
animal
antibody specificity
cell transformation
disease model
gene expression
gene targeting
gene vector
genetics
homologous recombination
liver cell carcinoma
liver tumor
metabolism
oncogene ras
pathology
signal transduction
transgenic animal
Wnt signaling pathway
zebra fish
Animals
Animals, Genetically Modified
Carcinoma, Hepatocellular
Cell Transformation, Neoplastic
Disease Models, Animal
Gene Expression
Gene Targeting
Genes, ras
Genetic Vectors
Homologous Recombination
Liver Neoplasms
MAP Kinase Signaling System
Organ Specificity
Recombinant Fusion Proteins
Wnt Signaling Pathway
Zebrafish
spellingShingle hybrid protein
animal
antibody specificity
cell transformation
disease model
gene expression
gene targeting
gene vector
genetics
homologous recombination
liver cell carcinoma
liver tumor
metabolism
oncogene ras
pathology
signal transduction
transgenic animal
Wnt signaling pathway
zebra fish
Animals
Animals, Genetically Modified
Carcinoma, Hepatocellular
Cell Transformation, Neoplastic
Disease Models, Animal
Gene Expression
Gene Targeting
Genes, ras
Genetic Vectors
Homologous Recombination
Liver Neoplasms
MAP Kinase Signaling System
Organ Specificity
Recombinant Fusion Proteins
Wnt Signaling Pathway
Zebrafish
Nguyen A.T.
Koh V.
Spitsbergen J.M.
Gong Z.
Development of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic kras V12 expression in transgenic zebrafish
description 10.1038/srep19559
author2 BIOCHEMISTRY
author_facet BIOCHEMISTRY
Nguyen A.T.
Koh V.
Spitsbergen J.M.
Gong Z.
format Article
author Nguyen A.T.
Koh V.
Spitsbergen J.M.
Gong Z.
author_sort Nguyen A.T.
title Development of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic kras V12 expression in transgenic zebrafish
title_short Development of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic kras V12 expression in transgenic zebrafish
title_full Development of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic kras V12 expression in transgenic zebrafish
title_fullStr Development of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic kras V12 expression in transgenic zebrafish
title_full_unstemmed Development of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic kras V12 expression in transgenic zebrafish
title_sort development of a conditional liver tumor model by mifepristone-inducible cre recombination to control oncogenic kras v12 expression in transgenic zebrafish
publisher Nature Publishing Group
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/175440
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