Co-infection with Chikungunya virus alters trafficking of pathogenic CD8+ T cells into the brain and prevents Plasmodium-induced neuropathology

Co-infection with Chikungunya virus alters trafficking of pathogenic CD8+ T cells into the brain and prevents Plasmodium-induced neuropathology

10.15252/emmm.201707885

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Bibliographic Details
Main Authors:	Teo, T.-H, Howland, S.W, Claser, C, Gun, S.Y, Poh, C.M, Lee, W.W.L, Lum, F.-M, Ng, L.F.P, Rénia, L
Other Authors:	DEPT OF BIOCHEMISTRY
Format:	Article
Published:	2020
Subjects:	chemokine receptor CXCR3 CXCL9 chemokine gamma interferon gamma interferon inducible protein 10 leukosialin animal experiment animal model animal tissue Article blood brain barrier CD8+ T lymphocyte cerebral malaria Chikungunya virus controlled study cross presentation cytokine production female infection sensitivity lymphocyte migration male mixed infection mortality rate mouse neuropathology nonhuman Plasmodium Plasmodium berghei infection priority journal protein expression animal brain C57BL mouse cell motion chikungunya parasitology pathology physiology Plasmodium berghei protection virology Animals Brain CD8-Positive T-Lymphocytes Cell Movement Chikungunya Fever Coinfection Female Malaria, Cerebral Male Mice Mice, Inbred C57BL Neuropathology Protective Factors
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/178125
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Institution:	National University of Singapore

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Summary:	10.15252/emmm.201707885