Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome

• Main Authors: Neilsen, P.M, Noll, J.E, Suetani, R.J, Schulz, R.B, Al-Ejeh, F, Evdokiou, A, Lane, D.P, Callen, D.F
• Other Authors: MEDICINE
• Format: Article
• Published: Impact Journals 2020
• Subjects: protein p53; TP53 protein, human; TP63 protein, human; transcription factor; transcriptome; tumor suppressor protein; article; cancer invasion; cell cycle; cell proliferation; gene expression regulation; genetic transcription; genetics; human; metabolism; signal transduction; transcription initiation; tumor cell line; tumor microenvironment; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Invasiveness; Signal Transduction; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Tumor Microenvironment; Tumor Suppressor Protein p53; Tumor Suppressor Proteins
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178184
• Institution: National University of Singapore

10.18632/oncotarget.382