Dimerisation of HIV-2 genomic RNA is linked to efficient RNA packaging, normal particle maturation and viral infectivity

• Main Authors: L'Hernault, A, Greatorex, J.S, Crowther, R.A, Lever, A.M.L
• Other Authors: MEDICINE
• Format: Article
• Published: BMC 2020
• Subjects: genomic RNA; mutant protein; virus RNA; article; controlled study; dimerization; electron microscopy; gene deletion; Human immunodeficiency virus 2; in vivo study; mutational analysis; nonhuman; RNA analysis; RNA processing; RNA sequence; signal transduction; virion; virus infectivity; virus particle; virus replication; animal; cell strain COS1; Cercopithecus; conformation; human; leukemia cell line; metabolism; molecular genetics; nucleotide sequence; pathogenicity; physiology; tumor cell line; Animals; Base Sequence; Cell Line, Tumor; Cercopithecus aethiops; COS Cells; Dimerization; HIV-2; Humans; Jurkat Cells; Molecular Sequence Data; Nucleic Acid Conformation; RNA, Viral; Virus Replication
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178239
• Institution: National University of Singapore

10.1186/1742-4690-4-90