Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery

Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery

10.1038/s41598-017-01712-5

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Bibliographic Details
Main Authors:	Thean, D, Ebo, J.S, Luxton, T, Lee, X.C, Yuen, T.Y, Ferrer, F.J, Johannes, C.W, Lane, D.P, Brown, C.J
Other Authors:	MEDICINE
Format:	Article
Published:	2020
Subjects:	cation hydrocarbon lipid multiprotein complex peptide protein MDM2 protein p53 pyridine derivative cell survival chemistry drug delivery system endosome genetics HEK293 cell line human IC50 intracellular space metabolism peptide library reporter gene transcription initiation Cations Cell Survival Drug Delivery Systems Endosomes Genes, Reporter HEK293 Cells Humans Hydrocarbons Inhibitory Concentration 50 Intracellular Space Lipids Multiprotein Complexes Peptide Library Peptides Proto-Oncogene Proteins c-mdm2 Pyridines Transcriptional Activation Tumor Suppressor Protein p53
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/178325
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Institution:	National University of Singapore

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Summary:	10.1038/s41598-017-01712-5