Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery

10.1038/s41598-017-01712-5

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Main Authors: Thean, D, Ebo, J.S, Luxton, T, Lee, X.C, Yuen, T.Y, Ferrer, F.J, Johannes, C.W, Lane, D.P, Brown, C.J
Other Authors: MEDICINE
Format: Article
Published: 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/178325
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spelling sg-nus-scholar.10635-1783252024-04-18T03:03:39Z Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery Thean, D Ebo, J.S Luxton, T Lee, X.C Yuen, T.Y Ferrer, F.J Johannes, C.W Lane, D.P Brown, C.J MEDICINE cation hydrocarbon lipid multiprotein complex peptide protein MDM2 protein p53 pyridine derivative cell survival chemistry drug delivery system endosome genetics HEK293 cell line human IC50 intracellular space metabolism peptide library reporter gene transcription initiation Cations Cell Survival Drug Delivery Systems Endosomes Genes, Reporter HEK293 Cells Humans Hydrocarbons Inhibitory Concentration 50 Intracellular Space Lipids Multiprotein Complexes Peptide Library Peptides Proto-Oncogene Proteins c-mdm2 Pyridines Transcriptional Activation Tumor Suppressor Protein p53 10.1038/s41598-017-01712-5 Scientific Reports 7 1 1763 2020-10-20T09:13:47Z 2020-10-20T09:13:47Z 2017 Article Thean, D, Ebo, J.S, Luxton, T, Lee, X.C, Yuen, T.Y, Ferrer, F.J, Johannes, C.W, Lane, D.P, Brown, C.J (2017). Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery. Scientific Reports 7 (1) : 1763. ScholarBank@NUS Repository. https://doi.org/10.1038/s41598-017-01712-5 20452322 https://scholarbank.nus.edu.sg/handle/10635/178325 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic cation
hydrocarbon
lipid
multiprotein complex
peptide
protein MDM2
protein p53
pyridine derivative
cell survival
chemistry
drug delivery system
endosome
genetics
HEK293 cell line
human
IC50
intracellular space
metabolism
peptide library
reporter gene
transcription initiation
Cations
Cell Survival
Drug Delivery Systems
Endosomes
Genes, Reporter
HEK293 Cells
Humans
Hydrocarbons
Inhibitory Concentration 50
Intracellular Space
Lipids
Multiprotein Complexes
Peptide Library
Peptides
Proto-Oncogene Proteins c-mdm2
Pyridines
Transcriptional Activation
Tumor Suppressor Protein p53
spellingShingle cation
hydrocarbon
lipid
multiprotein complex
peptide
protein MDM2
protein p53
pyridine derivative
cell survival
chemistry
drug delivery system
endosome
genetics
HEK293 cell line
human
IC50
intracellular space
metabolism
peptide library
reporter gene
transcription initiation
Cations
Cell Survival
Drug Delivery Systems
Endosomes
Genes, Reporter
HEK293 Cells
Humans
Hydrocarbons
Inhibitory Concentration 50
Intracellular Space
Lipids
Multiprotein Complexes
Peptide Library
Peptides
Proto-Oncogene Proteins c-mdm2
Pyridines
Transcriptional Activation
Tumor Suppressor Protein p53
Thean, D
Ebo, J.S
Luxton, T
Lee, X.C
Yuen, T.Y
Ferrer, F.J
Johannes, C.W
Lane, D.P
Brown, C.J
Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery
description 10.1038/s41598-017-01712-5
author2 MEDICINE
author_facet MEDICINE
Thean, D
Ebo, J.S
Luxton, T
Lee, X.C
Yuen, T.Y
Ferrer, F.J
Johannes, C.W
Lane, D.P
Brown, C.J
format Article
author Thean, D
Ebo, J.S
Luxton, T
Lee, X.C
Yuen, T.Y
Ferrer, F.J
Johannes, C.W
Lane, D.P
Brown, C.J
author_sort Thean, D
title Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery
title_short Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery
title_full Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery
title_fullStr Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery
title_full_unstemmed Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery
title_sort enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/178325
_version_ 1800914490334642176