Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery
10.1038/s41598-017-01712-5
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sg-nus-scholar.10635-1783252024-04-18T03:03:39Z Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery Thean, D Ebo, J.S Luxton, T Lee, X.C Yuen, T.Y Ferrer, F.J Johannes, C.W Lane, D.P Brown, C.J MEDICINE cation hydrocarbon lipid multiprotein complex peptide protein MDM2 protein p53 pyridine derivative cell survival chemistry drug delivery system endosome genetics HEK293 cell line human IC50 intracellular space metabolism peptide library reporter gene transcription initiation Cations Cell Survival Drug Delivery Systems Endosomes Genes, Reporter HEK293 Cells Humans Hydrocarbons Inhibitory Concentration 50 Intracellular Space Lipids Multiprotein Complexes Peptide Library Peptides Proto-Oncogene Proteins c-mdm2 Pyridines Transcriptional Activation Tumor Suppressor Protein p53 10.1038/s41598-017-01712-5 Scientific Reports 7 1 1763 2020-10-20T09:13:47Z 2020-10-20T09:13:47Z 2017 Article Thean, D, Ebo, J.S, Luxton, T, Lee, X.C, Yuen, T.Y, Ferrer, F.J, Johannes, C.W, Lane, D.P, Brown, C.J (2017). Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery. Scientific Reports 7 (1) : 1763. ScholarBank@NUS Repository. https://doi.org/10.1038/s41598-017-01712-5 20452322 https://scholarbank.nus.edu.sg/handle/10635/178325 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031 |
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cation hydrocarbon lipid multiprotein complex peptide protein MDM2 protein p53 pyridine derivative cell survival chemistry drug delivery system endosome genetics HEK293 cell line human IC50 intracellular space metabolism peptide library reporter gene transcription initiation Cations Cell Survival Drug Delivery Systems Endosomes Genes, Reporter HEK293 Cells Humans Hydrocarbons Inhibitory Concentration 50 Intracellular Space Lipids Multiprotein Complexes Peptide Library Peptides Proto-Oncogene Proteins c-mdm2 Pyridines Transcriptional Activation Tumor Suppressor Protein p53 |
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cation hydrocarbon lipid multiprotein complex peptide protein MDM2 protein p53 pyridine derivative cell survival chemistry drug delivery system endosome genetics HEK293 cell line human IC50 intracellular space metabolism peptide library reporter gene transcription initiation Cations Cell Survival Drug Delivery Systems Endosomes Genes, Reporter HEK293 Cells Humans Hydrocarbons Inhibitory Concentration 50 Intracellular Space Lipids Multiprotein Complexes Peptide Library Peptides Proto-Oncogene Proteins c-mdm2 Pyridines Transcriptional Activation Tumor Suppressor Protein p53 Thean, D Ebo, J.S Luxton, T Lee, X.C Yuen, T.Y Ferrer, F.J Johannes, C.W Lane, D.P Brown, C.J Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery |
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10.1038/s41598-017-01712-5 |
author2 |
MEDICINE |
author_facet |
MEDICINE Thean, D Ebo, J.S Luxton, T Lee, X.C Yuen, T.Y Ferrer, F.J Johannes, C.W Lane, D.P Brown, C.J |
format |
Article |
author |
Thean, D Ebo, J.S Luxton, T Lee, X.C Yuen, T.Y Ferrer, F.J Johannes, C.W Lane, D.P Brown, C.J |
author_sort |
Thean, D |
title |
Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery |
title_short |
Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery |
title_full |
Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery |
title_fullStr |
Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery |
title_full_unstemmed |
Enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery |
title_sort |
enhancing specific disruption of intracellular protein complexes by hydrocarbon stapled peptides using lipid based delivery |
publishDate |
2020 |
url |
https://scholarbank.nus.edu.sg/handle/10635/178325 |
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1800914490334642176 |