NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans

NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans

10.1038/s41598-017-09177-2

Saved in:

Bibliographic Details
Main Authors:	Gengenbacher, M, Duque-Correa, M.A, Kaiser, P, Schuerer, S, Lazar, D, Zedler, U, Reece, S.T, Nayyar, A, Cole, S.T, Makarov, V, Barry, C.E, Dartois, V, Kaufmann, S.H.E
Other Authors:	MEDICINE
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	inducible nitric oxide synthase isoniazid Nos2 protein, mouse rifampicin rifapentine tuberculostatic agent analogs and derivatives animal deficiency disease model fibrosis foam cell genetics human hypoxia immunology knockout mouse lung tuberculosis metabolism mouse necrosis pathology treatment outcome Animals Antitubercular Agents Disease Models, Animal Fibrosis Foam Cells Humans Hypoxia Isoniazid Mice Mice, Knockout Necrosis Nitric Oxide Synthase Type II Rifampin Treatment Outcome Tuberculosis, Pulmonary
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/178592
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

Description
Summary:	10.1038/s41598-017-09177-2