NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans

10.1038/s41598-017-09177-2

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Main Authors:	Gengenbacher, M, Duque-Correa, M.A, Kaiser, P, Schuerer, S, Lazar, D, Zedler, U, Reece, S.T, Nayyar, A, Cole, S.T, Makarov, V, Barry, C.E, Dartois, V, Kaufmann, S.H.E
Other Authors:	MEDICINE
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	inducible nitric oxide synthase isoniazid Nos2 protein, mouse rifampicin rifapentine tuberculostatic agent analogs and derivatives animal deficiency disease model fibrosis foam cell genetics human hypoxia immunology knockout mouse lung tuberculosis metabolism mouse necrosis pathology treatment outcome Animals Antitubercular Agents Disease Models, Animal Fibrosis Foam Cells Humans Hypoxia Isoniazid Mice Mice, Knockout Necrosis Nitric Oxide Synthase Type II Rifampin Treatment Outcome Tuberculosis, Pulmonary
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/178592
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1785922024-04-24T05:50:37Z NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans Gengenbacher, M Duque-Correa, M.A Kaiser, P Schuerer, S Lazar, D Zedler, U Reece, S.T Nayyar, A Cole, S.T Makarov, V Barry, C.E Dartois, V Kaufmann, S.H.E MEDICINE inducible nitric oxide synthase isoniazid Nos2 protein, mouse rifampicin rifapentine tuberculostatic agent analogs and derivatives animal deficiency disease model fibrosis foam cell genetics human hypoxia immunology knockout mouse lung tuberculosis metabolism mouse necrosis pathology treatment outcome Animals Antitubercular Agents Disease Models, Animal Fibrosis Foam Cells Humans Hypoxia Isoniazid Mice Mice, Knockout Necrosis Nitric Oxide Synthase Type II Rifampin Treatment Outcome Tuberculosis, Pulmonary 10.1038/s41598-017-09177-2 Scientific Reports 7 1 8853 2020-10-20T10:27:40Z 2020-10-20T10:27:40Z 2017 Article Gengenbacher, M, Duque-Correa, M.A, Kaiser, P, Schuerer, S, Lazar, D, Zedler, U, Reece, S.T, Nayyar, A, Cole, S.T, Makarov, V, Barry, C.E, Dartois, V, Kaufmann, S.H.E (2017). NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans. Scientific Reports 7 (1) : 8853. ScholarBank@NUS Repository. https://doi.org/10.1038/s41598-017-09177-2 2045-2322 https://scholarbank.nus.edu.sg/handle/10635/178592 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	inducible nitric oxide synthase isoniazid Nos2 protein, mouse rifampicin rifapentine tuberculostatic agent analogs and derivatives animal deficiency disease model fibrosis foam cell genetics human hypoxia immunology knockout mouse lung tuberculosis metabolism mouse necrosis pathology treatment outcome Animals Antitubercular Agents Disease Models, Animal Fibrosis Foam Cells Humans Hypoxia Isoniazid Mice Mice, Knockout Necrosis Nitric Oxide Synthase Type II Rifampin Treatment Outcome Tuberculosis, Pulmonary
spellingShingle	inducible nitric oxide synthase isoniazid Nos2 protein, mouse rifampicin rifapentine tuberculostatic agent analogs and derivatives animal deficiency disease model fibrosis foam cell genetics human hypoxia immunology knockout mouse lung tuberculosis metabolism mouse necrosis pathology treatment outcome Animals Antitubercular Agents Disease Models, Animal Fibrosis Foam Cells Humans Hypoxia Isoniazid Mice Mice, Knockout Necrosis Nitric Oxide Synthase Type II Rifampin Treatment Outcome Tuberculosis, Pulmonary Gengenbacher, M Duque-Correa, M.A Kaiser, P Schuerer, S Lazar, D Zedler, U Reece, S.T Nayyar, A Cole, S.T Makarov, V Barry, C.E Dartois, V Kaufmann, S.H.E NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans
description	10.1038/s41598-017-09177-2
author2	MEDICINE
author_facet	MEDICINE Gengenbacher, M Duque-Correa, M.A Kaiser, P Schuerer, S Lazar, D Zedler, U Reece, S.T Nayyar, A Cole, S.T Makarov, V Barry, C.E Dartois, V Kaufmann, S.H.E
format	Article
author	Gengenbacher, M Duque-Correa, M.A Kaiser, P Schuerer, S Lazar, D Zedler, U Reece, S.T Nayyar, A Cole, S.T Makarov, V Barry, C.E Dartois, V Kaufmann, S.H.E
author_sort	Gengenbacher, M
title	NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans
title_short	NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans
title_full	NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans
title_fullStr	NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans
title_full_unstemmed	NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans
title_sort	nos2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/178592
_version_	1800914511492808704

NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans

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