Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis

10.1186/s12974-017-0801-1

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Main Authors:	Ong, C.W.M, Pabisiak, P.J, Brilha, S, Singh, P, Roncaroli, F, Elkington, P.T, Friedland, J.S
Other Authors:	MEDICINE
Format:	Article
Published:	2020
Subjects:	collagen type 4 dexamethasone gelatinase B immunoglobulin enhancer binding protein leukocyte elastase mitogen activated protein kinase mitogen activated protein kinase p38 neutrophil collagenase phosphatidylinositol 3 kinase protein kinase B protein S 100 tumor necrosis factor 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one antibody chromone derivative enzyme inhibitor morpholine derivative oncoprotein peroxidase Article bacterium culture basement membrane blood brain barrier brain biopsy cell viability central nervous system tuberculosis collagen degradation confocal microscopy controlled study enzyme linked immunosorbent assay fluorescence activated cell sorting gene expression genotype histopathology human human experiment immunofluorescence microscopy immunohistochemistry immunopathology macrophage monocyte Mycobacterium tuberculosis neutrophil neutrophil count normal human protein secretion real time polymerase chain reaction signal transduction supernatant upregulation cell culture dose response drug effects female gene expression regulation genetics immunology leukocyte male metabolism pathology physiology secretion (process) Antibodies Cells, Cultured Chromones Collagen Type IV Dose-Response Relationship, Drug Enzyme Inhibitors Female Gene Expression Regulation, Bacterial Humans Leukocytes Male Matrix Metalloproteinase 9 Morpholines Neutrophils NF-kappa B Oncogene Protein v-akt Peroxidase Signal Transduction Tuberculosis, Central Nervous System Up-Regulation
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/179530
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1795302024-04-24T05:54:06Z Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis Ong, C.W.M Pabisiak, P.J Brilha, S Singh, P Roncaroli, F Elkington, P.T Friedland, J.S MEDICINE collagen type 4 dexamethasone gelatinase B immunoglobulin enhancer binding protein leukocyte elastase mitogen activated protein kinase mitogen activated protein kinase p38 neutrophil collagenase phosphatidylinositol 3 kinase protein kinase B protein S 100 tumor necrosis factor 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one antibody chromone derivative collagen type 4 enzyme inhibitor gelatinase B immunoglobulin enhancer binding protein morpholine derivative oncoprotein peroxidase Article bacterium culture basement membrane blood brain barrier brain biopsy cell viability central nervous system tuberculosis collagen degradation confocal microscopy controlled study enzyme linked immunosorbent assay fluorescence activated cell sorting gene expression genotype histopathology human human experiment immunofluorescence microscopy immunohistochemistry immunopathology macrophage monocyte Mycobacterium tuberculosis neutrophil neutrophil count normal human protein secretion real time polymerase chain reaction signal transduction supernatant upregulation cell culture central nervous system tuberculosis dose response drug effects female gene expression regulation genetics immunology leukocyte male metabolism neutrophil pathology physiology secretion (process) Antibodies Cells, Cultured Chromones Collagen Type IV Dose-Response Relationship, Drug Enzyme Inhibitors Female Gene Expression Regulation, Bacterial Humans Leukocytes Male Matrix Metalloproteinase 9 Morpholines Mycobacterium tuberculosis Neutrophils NF-kappa B Oncogene Protein v-akt Peroxidase Signal Transduction Tuberculosis, Central Nervous System Up-Regulation 10.1186/s12974-017-0801-1 Journal of Neuroinflammation 14 1 31 2020-10-23T04:52:52Z 2020-10-23T04:52:52Z 2017 Article Ong, C.W.M, Pabisiak, P.J, Brilha, S, Singh, P, Roncaroli, F, Elkington, P.T, Friedland, J.S (2017). Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis. Journal of Neuroinflammation 14 (1) : 31. ScholarBank@NUS Repository. https://doi.org/10.1186/s12974-017-0801-1 17422094 https://scholarbank.nus.edu.sg/handle/10635/179530 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	collagen type 4 dexamethasone gelatinase B immunoglobulin enhancer binding protein leukocyte elastase mitogen activated protein kinase mitogen activated protein kinase p38 neutrophil collagenase phosphatidylinositol 3 kinase protein kinase B protein S 100 tumor necrosis factor 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one antibody chromone derivative collagen type 4 enzyme inhibitor gelatinase B immunoglobulin enhancer binding protein morpholine derivative oncoprotein peroxidase Article bacterium culture basement membrane blood brain barrier brain biopsy cell viability central nervous system tuberculosis collagen degradation confocal microscopy controlled study enzyme linked immunosorbent assay fluorescence activated cell sorting gene expression genotype histopathology human human experiment immunofluorescence microscopy immunohistochemistry immunopathology macrophage monocyte Mycobacterium tuberculosis neutrophil neutrophil count normal human protein secretion real time polymerase chain reaction signal transduction supernatant upregulation cell culture central nervous system tuberculosis dose response drug effects female gene expression regulation genetics immunology leukocyte male metabolism neutrophil pathology physiology secretion (process) Antibodies Cells, Cultured Chromones Collagen Type IV Dose-Response Relationship, Drug Enzyme Inhibitors Female Gene Expression Regulation, Bacterial Humans Leukocytes Male Matrix Metalloproteinase 9 Morpholines Mycobacterium tuberculosis Neutrophils NF-kappa B Oncogene Protein v-akt Peroxidase Signal Transduction Tuberculosis, Central Nervous System Up-Regulation
spellingShingle	collagen type 4 dexamethasone gelatinase B immunoglobulin enhancer binding protein leukocyte elastase mitogen activated protein kinase mitogen activated protein kinase p38 neutrophil collagenase phosphatidylinositol 3 kinase protein kinase B protein S 100 tumor necrosis factor 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one antibody chromone derivative collagen type 4 enzyme inhibitor gelatinase B immunoglobulin enhancer binding protein morpholine derivative oncoprotein peroxidase Article bacterium culture basement membrane blood brain barrier brain biopsy cell viability central nervous system tuberculosis collagen degradation confocal microscopy controlled study enzyme linked immunosorbent assay fluorescence activated cell sorting gene expression genotype histopathology human human experiment immunofluorescence microscopy immunohistochemistry immunopathology macrophage monocyte Mycobacterium tuberculosis neutrophil neutrophil count normal human protein secretion real time polymerase chain reaction signal transduction supernatant upregulation cell culture central nervous system tuberculosis dose response drug effects female gene expression regulation genetics immunology leukocyte male metabolism neutrophil pathology physiology secretion (process) Antibodies Cells, Cultured Chromones Collagen Type IV Dose-Response Relationship, Drug Enzyme Inhibitors Female Gene Expression Regulation, Bacterial Humans Leukocytes Male Matrix Metalloproteinase 9 Morpholines Mycobacterium tuberculosis Neutrophils NF-kappa B Oncogene Protein v-akt Peroxidase Signal Transduction Tuberculosis, Central Nervous System Up-Regulation Ong, C.W.M Pabisiak, P.J Brilha, S Singh, P Roncaroli, F Elkington, P.T Friedland, J.S Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis
description	10.1186/s12974-017-0801-1
author2	MEDICINE
author_facet	MEDICINE Ong, C.W.M Pabisiak, P.J Brilha, S Singh, P Roncaroli, F Elkington, P.T Friedland, J.S
format	Article
author	Ong, C.W.M Pabisiak, P.J Brilha, S Singh, P Roncaroli, F Elkington, P.T Friedland, J.S
author_sort	Ong, C.W.M
title	Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis
title_short	Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis
title_full	Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis
title_fullStr	Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis
title_full_unstemmed	Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis
title_sort	complex regulation of neutrophil-derived mmp-9 secretion in central nervous system tuberculosis
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/179530
_version_	1800914555933556736

Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis

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