Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis
10.1007/s00109-015-1358-z
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2020
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sg-nus-scholar.10635-1795942024-11-15T21:19:32Z Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis Seet, L.-F Toh, L.Z Finger, S.N Chu, S.W.L Stefanovic, B Wong, T.T DUKE-NUS MEDICAL SCHOOL alpha smooth muscle actin beta actin collagen type 1 messenger RNA short hairpin RNA Smad protein Smad2 protein Smad4 protein Smad6 protein tenascin transforming growth factor beta2 valproic acid collagen type 1 enzyme inhibitor Smad protein transforming growth factor beta2 valproic acid animal cell animal experiment animal model apoptosis Article cell differentiation cell viability collagen fiber conjunctiva disease conjunctival fibrosis fibroblast fibrosis filtering operation glaucoma mouse myofibroblast nonhuman phenotype promoter region protein expression regulatory mechanism steady state wound healing animal C57BL mouse cell culture complication conjunctiva drug effects fibrosis gene expression regulation genetics glaucoma metabolism pathology Animals Cells, Cultured Collagen Type I Conjunctiva Enzyme Inhibitors Fibroblasts Fibrosis Gene Expression Regulation Glaucoma Mice Mice, Inbred C57BL Smad Proteins Transforming Growth Factor beta2 Valproic Acid 10.1007/s00109-015-1358-z Journal of Molecular Medicine 94 3 321-334 2020-10-23T07:58:35Z 2020-10-23T07:58:35Z 2016 Article Seet, L.-F, Toh, L.Z, Finger, S.N, Chu, S.W.L, Stefanovic, B, Wong, T.T (2016). Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis. Journal of Molecular Medicine 94 (3) : 321-334. ScholarBank@NUS Repository. https://doi.org/10.1007/s00109-015-1358-z 0946-2716 https://scholarbank.nus.edu.sg/handle/10635/179594 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Springer Verlag Unpaywall 20201031 |
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alpha smooth muscle actin beta actin collagen type 1 messenger RNA short hairpin RNA Smad protein Smad2 protein Smad4 protein Smad6 protein tenascin transforming growth factor beta2 valproic acid collagen type 1 enzyme inhibitor Smad protein transforming growth factor beta2 valproic acid animal cell animal experiment animal model apoptosis Article cell differentiation cell viability collagen fiber conjunctiva disease conjunctival fibrosis fibroblast fibrosis filtering operation glaucoma mouse myofibroblast nonhuman phenotype promoter region protein expression regulatory mechanism steady state wound healing animal C57BL mouse cell culture complication conjunctiva drug effects fibrosis gene expression regulation genetics glaucoma metabolism pathology Animals Cells, Cultured Collagen Type I Conjunctiva Enzyme Inhibitors Fibroblasts Fibrosis Gene Expression Regulation Glaucoma Mice Mice, Inbred C57BL Smad Proteins Transforming Growth Factor beta2 Valproic Acid |
| spellingShingle |
alpha smooth muscle actin beta actin collagen type 1 messenger RNA short hairpin RNA Smad protein Smad2 protein Smad4 protein Smad6 protein tenascin transforming growth factor beta2 valproic acid collagen type 1 enzyme inhibitor Smad protein transforming growth factor beta2 valproic acid animal cell animal experiment animal model apoptosis Article cell differentiation cell viability collagen fiber conjunctiva disease conjunctival fibrosis fibroblast fibrosis filtering operation glaucoma mouse myofibroblast nonhuman phenotype promoter region protein expression regulatory mechanism steady state wound healing animal C57BL mouse cell culture complication conjunctiva drug effects fibrosis gene expression regulation genetics glaucoma metabolism pathology Animals Cells, Cultured Collagen Type I Conjunctiva Enzyme Inhibitors Fibroblasts Fibrosis Gene Expression Regulation Glaucoma Mice Mice, Inbred C57BL Smad Proteins Transforming Growth Factor beta2 Valproic Acid Seet, L.-F Toh, L.Z Finger, S.N Chu, S.W.L Stefanovic, B Wong, T.T Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis |
| description |
10.1007/s00109-015-1358-z |
| author2 |
DUKE-NUS MEDICAL SCHOOL |
| author_facet |
DUKE-NUS MEDICAL SCHOOL Seet, L.-F Toh, L.Z Finger, S.N Chu, S.W.L Stefanovic, B Wong, T.T |
| format |
Article |
| author |
Seet, L.-F Toh, L.Z Finger, S.N Chu, S.W.L Stefanovic, B Wong, T.T |
| author_sort |
Seet, L.-F |
| title |
Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis |
| title_short |
Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis |
| title_full |
Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis |
| title_fullStr |
Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis |
| title_full_unstemmed |
Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis |
| title_sort |
valproic acid suppresses collagen by selective regulation of smads in conjunctival fibrosis |
| publisher |
Springer Verlag |
| publishDate |
2020 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/179594 |
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1821234668335267840 |