Structure of the NS2B-NS3 protease from Zika virus after self-cleavage

10.1038/ncomms13410

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Bibliographic Details
Main Authors:	Phoo, W.W, Li, Y, Zhang, Z, Lee, M.Y, Loh, Y.R, Tan, Y.B, Ng, E.Y, Lescar, J, Kang, C, Luo, D
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	nonstructural protein 2B nonstructural protein 3 polyprotein protease inhibitor BPTI proteinase proteinase inhibitor structural protein unclassified drug peptide hydrolase protein binding viral protein amino acid crystal structure nuclear magnetic resonance population outbreak protein public health substrate viral disease virus Article carboxy terminal sequence comparative study controlled study enzyme active site enzyme activity enzyme assay enzyme inhibition enzyme structure molecular recognition nonhuman protein degradation protein expression protein processing Zika virus binding site chemistry human metabolism molecular model nuclear magnetic resonance spectroscopy protein conformation X ray crystallography North America South America Flavivirus Binding Sites Catalytic Domain Crystallography, X-Ray Humans Magnetic Resonance Spectroscopy Models, Molecular Peptide Hydrolases Protein Binding Protein Conformation Proteolysis Viral Nonstructural Proteins Zika Virus
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/179788
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Institution:	National University of Singapore

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