Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS

10.1186/s40478-015-0212-4

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Main Authors:	Mitchell, J.C, Constable, R, So, E, Vance, C, Scotter, E, Glover, L, Hortobagyi, T, Arnold, E.S, Ling, S.-C, McAlonis, M, Da Cruz, S, Polymenidou, M, Tessarolo, L, Cleveland, D.W, Shaw, C.E
Other Authors:	PHYSIOLOGY
Format:	Article
Published:	2020
Subjects:	DNA binding protein leukocyte antigen nerve protein TDP-43 protein, human age amyotrophic lateral sclerosis animal brain cortex C57BL mouse cytoplasm disease course disease model gene expression regulation genetics human metabolism mouse mutation nerve cell pathology pathophysiology spinal cord transgenic mouse Age Factors Amyotrophic Lateral Sclerosis Animals Antigens, CD Cerebral Cortex Cytoplasm Disease Models, Animal Disease Progression DNA-Binding Proteins Gene Expression Regulation Humans Mice Mice, Inbred C57BL Mice, Transgenic Mutation Nerve Tissue Proteins Neurons Spinal Cord
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/180330
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1803302024-11-11T21:39:09Z Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS Mitchell, J.C Constable, R So, E Vance, C Scotter, E Glover, L Hortobagyi, T Arnold, E.S Ling, S.-C McAlonis, M Da Cruz, S Polymenidou, M Tessarolo, L Cleveland, D.W Shaw, C.E PHYSIOLOGY DNA binding protein leukocyte antigen nerve protein TDP-43 protein, human age amyotrophic lateral sclerosis animal brain cortex C57BL mouse cytoplasm disease course disease model gene expression regulation genetics human metabolism mouse mutation nerve cell pathology pathophysiology spinal cord transgenic mouse Age Factors Amyotrophic Lateral Sclerosis Animals Antigens, CD Cerebral Cortex Cytoplasm Disease Models, Animal Disease Progression DNA-Binding Proteins Gene Expression Regulation Humans Mice Mice, Inbred C57BL Mice, Transgenic Mutation Nerve Tissue Proteins Neurons Spinal Cord 10.1186/s40478-015-0212-4 Acta neuropathologica communications 3 36 2020-10-26T08:29:43Z 2020-10-26T08:29:43Z 2015 Article Mitchell, J.C, Constable, R, So, E, Vance, C, Scotter, E, Glover, L, Hortobagyi, T, Arnold, E.S, Ling, S.-C, McAlonis, M, Da Cruz, S, Polymenidou, M, Tessarolo, L, Cleveland, D.W, Shaw, C.E (2015). Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS. Acta neuropathologica communications 3 : 36. ScholarBank@NUS Repository. https://doi.org/10.1186/s40478-015-0212-4 20515960 https://scholarbank.nus.edu.sg/handle/10635/180330 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	DNA binding protein leukocyte antigen nerve protein TDP-43 protein, human age amyotrophic lateral sclerosis animal brain cortex C57BL mouse cytoplasm disease course disease model gene expression regulation genetics human metabolism mouse mutation nerve cell pathology pathophysiology spinal cord transgenic mouse Age Factors Amyotrophic Lateral Sclerosis Animals Antigens, CD Cerebral Cortex Cytoplasm Disease Models, Animal Disease Progression DNA-Binding Proteins Gene Expression Regulation Humans Mice Mice, Inbred C57BL Mice, Transgenic Mutation Nerve Tissue Proteins Neurons Spinal Cord
spellingShingle	DNA binding protein leukocyte antigen nerve protein TDP-43 protein, human age amyotrophic lateral sclerosis animal brain cortex C57BL mouse cytoplasm disease course disease model gene expression regulation genetics human metabolism mouse mutation nerve cell pathology pathophysiology spinal cord transgenic mouse Age Factors Amyotrophic Lateral Sclerosis Animals Antigens, CD Cerebral Cortex Cytoplasm Disease Models, Animal Disease Progression DNA-Binding Proteins Gene Expression Regulation Humans Mice Mice, Inbred C57BL Mice, Transgenic Mutation Nerve Tissue Proteins Neurons Spinal Cord Mitchell, J.C Constable, R So, E Vance, C Scotter, E Glover, L Hortobagyi, T Arnold, E.S Ling, S.-C McAlonis, M Da Cruz, S Polymenidou, M Tessarolo, L Cleveland, D.W Shaw, C.E Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS
description	10.1186/s40478-015-0212-4
author2	PHYSIOLOGY
author_facet	PHYSIOLOGY Mitchell, J.C Constable, R So, E Vance, C Scotter, E Glover, L Hortobagyi, T Arnold, E.S Ling, S.-C McAlonis, M Da Cruz, S Polymenidou, M Tessarolo, L Cleveland, D.W Shaw, C.E
format	Article
author	Mitchell, J.C Constable, R So, E Vance, C Scotter, E Glover, L Hortobagyi, T Arnold, E.S Ling, S.-C McAlonis, M Da Cruz, S Polymenidou, M Tessarolo, L Cleveland, D.W Shaw, C.E
author_sort	Mitchell, J.C
title	Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS
title_short	Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS
title_full	Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS
title_fullStr	Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS
title_full_unstemmed	Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS
title_sort	wild type human tdp-43 potentiates als-linked mutant tdp-43 driven progressive motor and cortical neuron degeneration with pathological features of als
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/180330
_version_	1821181886739775488

Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS

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