Rumex dentatus inhibits cell proliferation, arrests cell cycle, and induces apoptosis in MDA-MB-231 cells through suppression of the NF-κB pathway

• Main Authors: Batool, R, Aziz, E, Tan, B.K.-H, Mahmood, T
• Other Authors: DEPT OF PHARMACOLOGY
• Format: Article
• Published: 2020
• Subjects: caspase 3; chloroform; cyclin D1; immunoglobulin enhancer binding protein; methanol; plant extract; protein bcl 2; protein bcl xl; Rumex dentatus extract; survivin; unclassified drug; X linked inhibitor of apoptosis; antineoplastic activity; apoptosis; Article; biological activity; cell cycle arrest; cell proliferation; concentration response; controlled study; drug cytotoxicity; drug mechanism; flow cytometry; G1 phase cell cycle checkpoint; human; human cell; MDA-MB-231 cell line; MTT assay; plant leaf; protein phosphorylation; Rumex dentatus; Western blotting; wound healing assay
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181243
• Institution: National University of Singapore

10.3389/fphar.2017.00731