Proteomic profiling of cellular steatosis with concomitant oxidative stress in vitro

• Main Authors: Lockman, K.A, Htun, V, Sinha, R, Treskes, P, Nelson, L.J, Martin, S.F, Rogers, S.M, Le Bihan, T, Hayes, P.C, Plevris, J.N
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: acetyl coenzyme A acetyltransferase; adenosine diphosphate ribosylation factor 3; alpha enolase; ammonia; apolipoprotein A1; apolipoprotein E; cell protein; chaperonin containing TCP1; cholestanetriol 26 monooxygenase; complement component C4a; elongation factor 1alpha; elongation factor 2; fatty acid binding protein; guanine nucleotide binding protein beta subunit; heat shock protein 70; hemoglobin alpha chain; hepatocyte nuclear factor 4alpha; histone H2A; initiation factor 5A; karyopherin; lactate dehydrogenase; lactic acid; octanoic acid; protein S 100; pyruvic acid; somatomedin C receptor; squalene synthase; TATA binding protein; zinc transporter; aldehyde reductase; carbonyl reductase; cholesterol; fatty acid; histone; octanoic acid derivative; Article; controlled study; down regulation; endoplasmic reticulum stress; fatty acid metabolism; fatty liver; gene ontology; hepatoblastoma cell line; high performance liquid chromatography; human; human cell; in vitro study; lipid metabolism; lipid peroxidation; lipotoxicity; mass spectrometry; nonalcoholic fatty liver; nutrient uptake; oxidative stress; protein analysis; protein binding; protein expression; protein folding; protein synthesis; proteomics; sterol metabolism; upregulation; biological model; biosynthesis; cytology; drug effects; gene expression profiling; gene expression regulation; genetics; lipogenesis; liver cell; metabolism; molecular genetics; pathology; tumor cell line; Aldehyde Reductase; Ammonia; Caprylates; Cell Line, Tumor; Cholesterol; Fatty Acids, Nonesterified; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Hepatocytes; Histones; Humans; Lactic Acid; Lipid Peroxidation; Lipogenesis; Models, Biological; Molecular Sequence Annotation; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Protein Biosynthesis; Proteomics; Pyruvic Acid
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181358
• Institution: National University of Singapore

10.1186/s12944-016-0283-7