Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error

• Main Authors: Fan, Q., Pozarickij, A., Tan, N.Y.Q., Guo, X., Verhoeven, V.J.M., Vitart, V., Guggenheim, J.A., Miyake, M., Tideman, J.W.L., Khawaja, A.P., Zhang, L., MacGregor, S., Höhn, R., Chen, P., Biino, G., Wedenoja, J., Saffari, S.E., Tedja, M.S., Xie, J., Lanca, C., Wang, Y.X., Sahebjada, S., Mazur, J., Mirshahi, A., Martin, N.G., Yazar, S., Pennell, C.E., Yap, M., Haarman, A.E.G., Enthoven, C.A., Polling, J.R., Bailey-Wilson, J.E., Veluchamy, A.B., Burdon, K.P., Campbell, H., Chen, L.J., Chew, E.Y., Craig, J.E., Cumberland, P.M., Deangelis, M.M., Delcourt, C., Ding, X., Evans, D.M., Gharahkhani, P., Iglesias, A.I., Haller, T., Han, X., Hoang, Q., Igo, R.P., Iyengar, S.K., Kähönen, M., Kaprio, J., Klein, B.E., Klein, R., Lass, J.H., Lee, K., Lehtimäki, T., Lewis, D.D., Li, Q., Li, S.-M., Lyytikäinen, L.-P., Meguro, A., Metspalu, A., Middlebrooks, C.D., Mizuki, N., Musolf, A.M., Nickels, S., Oexle, K., Pang, C.P., Paterson, A.D., Rahi, J.S., Raitakari, O., Rudan, I., Stambolian, D., Simpson, C.L., Wang, N., Bin Wei, W., Williams, K.M., Wilson, J.F., Wojciechowski, R., Yamashiro, K., Yam, J.C.S., Zhou, X., Aslam, T., Barman, S.A., Barrett, J.H., Bishop, P., Blows, P., Bunce, C., Carare, R.O., Chakravarthy, U., Chan, M., Chua, S.Y.L., Crabb, D.P., Day, A., Desai, P., Dhillon, B., Dick, A.D., Egan, C., Ennis, S., Fruttiger, M., Gallacher, J.E.J., Garway-Heath, D.F., Gibson, J., Gore, D., Hardcastle, A., Harding, S.P., Hogg, R.E., Keane, P.A., Khaw, S.P.T., Lascaratos, G., Lotery, A.J., Macgillivray, T., Mackie, S., Martin, K., McGaughey, M., McGuinness, B., McKay, G.J., McKibbin, M., Mitry, D., Moore, T., Morgan, J.E., Muthy, Z.A., O’Sullivan, E., Owen, C.G., Patel, P., Paterson, E., Peto, T., Petzold, A., Rudnikca, A.R., Self, J., Sivaprasad, S., Steel, D., Stratton, I., Strouthidis, N., Sudlow, C., Thomas, D., Trucco, E., Tufail, A., Vernon, S.A., Viswanathan, A.C., Williams, K., Woodside, J.V., Yates, M.M., Yip, J., Zheng, Y., Hewitt, A.W., Jaddoe, V.W.V., van Duijn, C.M., Hayward, C., Polasek, O., Tai, E.-S., Yoshikatsu, H., Hysi, P.G., Young, T.L., Tsujikawa, A., Wang, J.J., Mitchell, P., Pfeiffer, N., Pärssinen, O., Foster, P.J., Fossarello, M., Yip, S.P., Williams, C., Hammond, C.J., Jonas, J.B., He, M., Mackey, D.A., Wong, T.-Y., Klaver, C.C.W., Saw, S.-M., Baird, P.N., Cheng, C.-Y., Consortium for Refractive Error and Myopia (CREAM)., UK Biobank Eye and Vision Consortium.
• Other Authors: MEDICINE
• Format: Article
• Published: Nature Research 2021
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/198570
• Institution: National University of Singapore

10.1038/s42003-020-0802-y