Immunosuppression overcomes insulin- and vector-specific immune responses that limit efficacy of AAV2/8-mediated insulin gene therapy in NOD mice

Immunosuppression overcomes insulin- and vector-specific immune responses that limit efficacy of AAV2/8-mediated insulin gene therapy in NOD mice

10.1038/s41434-018-0052-5

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Bibliographic Details
Main Authors: Recino, Asha, Gan, Shu Uin, Sia, Kian Chuan, Sawyer, Yvonne, Trendell, Jenny, Kay, Richard, Gribble, Fiona M, Reimann, Frank, Foale, Rob, Notaridou, Maria, Holmes, Nick, Lever, Andrew, Lee, Kok Onn, Nathwani, Amit, Cooke, Anne, Calne, Roy, Wallberg, Maja
Other Authors: MEDICINE
Format: Article
Language:English
Published: NATURE PUBLISHING GROUP 2021
Subjects:
Science & Technology
Life Sciences & Biomedicine
Biochemistry & Molecular Biology
Biotechnology & Applied Microbiology
Genetics & Heredity
Medicine, Research & Experimental
Research & Experimental Medicine
ISLET GRAFTS
MURINE LIVER
CELLS
EXPRESSION
TOLERANCE
IDENTIFICATION
ACTIVATION
ANTI-CD4
REVERSAL
DELIVERY
Online Access:https://scholarbank.nus.edu.sg/handle/10635/205977
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Institution: National University of Singapore
Language: English

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https://scholarbank.nus.edu.sg/handle/10635/205977

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