Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma
10.3389/fonc.2021.709525
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FRONTIERS MEDIA SA
2022
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sg-nus-scholar.10635-2186582023-10-31T08:21:38Z Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma Wong, Rachel LY Wong, Megan RE Kuick, Chik Hong Saffari, Seyed Ehsan Wong, Meng Kang Tan, Sheng Hui Merchant, Khurshid Chang, Kenneth TE Thangavelu, Matan Periyasamy, Giridharan Chen, Zhi Xiong Iyer, Prasad Tan, Enrica EK Soh, Shui Yen Iyer, N Gopalakrishna Fan, Qiao Loh, Amos HP DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL) CANCER SCIENCE INSTITUTE OF SINGAPORE DUKE-NUS MEDICAL SCHOOL Science & Technology Life Sciences & Biomedicine Oncology neuroblastoma patient-derived culture copy number variations (CNV) Comprehensive genomic profiling (CGP) PI3K AKT pathway CDK (cyclin-dependent kinase) JAK-STAT cascade SEGMENTAL CHROMOSOMAL ALTERATIONS HUMAN TUMOR XENOGRAFTS IN-VITRO KINASE INHIBITOR MYCN PROTEIN CELL-LINE CANCER TARGET MODELS GROWTH 10.3389/fonc.2021.709525 FRONTIERS IN ONCOLOGY 11 2022-04-08T00:52:45Z 2022-04-08T00:52:45Z 2021-10-14 2022-04-08T00:02:31Z Article Wong, Rachel LY, Wong, Megan RE, Kuick, Chik Hong, Saffari, Seyed Ehsan, Wong, Meng Kang, Tan, Sheng Hui, Merchant, Khurshid, Chang, Kenneth TE, Thangavelu, Matan, Periyasamy, Giridharan, Chen, Zhi Xiong, Iyer, Prasad, Tan, Enrica EK, Soh, Shui Yen, Iyer, N Gopalakrishna, Fan, Qiao, Loh, Amos HP (2021-10-14). Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma. FRONTIERS IN ONCOLOGY 11. ScholarBank@NUS Repository. https://doi.org/10.3389/fonc.2021.709525 2234-943X 2234-943X https://scholarbank.nus.edu.sg/handle/10635/218658 en FRONTIERS MEDIA SA Elements |
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Singapore Singapore |
| content_provider |
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| collection |
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English |
| topic |
Science & Technology Life Sciences & Biomedicine Oncology neuroblastoma patient-derived culture copy number variations (CNV) Comprehensive genomic profiling (CGP) PI3K AKT pathway CDK (cyclin-dependent kinase) JAK-STAT cascade SEGMENTAL CHROMOSOMAL ALTERATIONS HUMAN TUMOR XENOGRAFTS IN-VITRO KINASE INHIBITOR MYCN PROTEIN CELL-LINE CANCER TARGET MODELS GROWTH |
| spellingShingle |
Science & Technology Life Sciences & Biomedicine Oncology neuroblastoma patient-derived culture copy number variations (CNV) Comprehensive genomic profiling (CGP) PI3K AKT pathway CDK (cyclin-dependent kinase) JAK-STAT cascade SEGMENTAL CHROMOSOMAL ALTERATIONS HUMAN TUMOR XENOGRAFTS IN-VITRO KINASE INHIBITOR MYCN PROTEIN CELL-LINE CANCER TARGET MODELS GROWTH Wong, Rachel LY Wong, Megan RE Kuick, Chik Hong Saffari, Seyed Ehsan Wong, Meng Kang Tan, Sheng Hui Merchant, Khurshid Chang, Kenneth TE Thangavelu, Matan Periyasamy, Giridharan Chen, Zhi Xiong Iyer, Prasad Tan, Enrica EK Soh, Shui Yen Iyer, N Gopalakrishna Fan, Qiao Loh, Amos HP Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma |
| description |
10.3389/fonc.2021.709525 |
| author2 |
DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL) |
| author_facet |
DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL) Wong, Rachel LY Wong, Megan RE Kuick, Chik Hong Saffari, Seyed Ehsan Wong, Meng Kang Tan, Sheng Hui Merchant, Khurshid Chang, Kenneth TE Thangavelu, Matan Periyasamy, Giridharan Chen, Zhi Xiong Iyer, Prasad Tan, Enrica EK Soh, Shui Yen Iyer, N Gopalakrishna Fan, Qiao Loh, Amos HP |
| format |
Article |
| author |
Wong, Rachel LY Wong, Megan RE Kuick, Chik Hong Saffari, Seyed Ehsan Wong, Meng Kang Tan, Sheng Hui Merchant, Khurshid Chang, Kenneth TE Thangavelu, Matan Periyasamy, Giridharan Chen, Zhi Xiong Iyer, Prasad Tan, Enrica EK Soh, Shui Yen Iyer, N Gopalakrishna Fan, Qiao Loh, Amos HP |
| author_sort |
Wong, Rachel LY |
| title |
Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma |
| title_short |
Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma |
| title_full |
Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma |
| title_fullStr |
Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma |
| title_full_unstemmed |
Integrated Genomic Profiling and Drug Screening of Patient-Derived Cultures Identifies Individualized Copy Number-Dependent Susceptibilities Involving PI3K Pathway and 17q Genes in Neuroblastoma |
| title_sort |
integrated genomic profiling and drug screening of patient-derived cultures identifies individualized copy number-dependent susceptibilities involving pi3k pathway and 17q genes in neuroblastoma |
| publisher |
FRONTIERS MEDIA SA |
| publishDate |
2022 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/218658 |
| _version_ |
1781793043076087808 |