A Single Amino Acid Substitution in Structural Protein VP2 Abrogates the Neurotropism of Enterovirus A-71 in Mice

• Main Authors: Yeo, Huimin, Chong, Connie Wan Hui, Chen, Elijah Weihua, Lim, Ze Qin, Ng, Qing Yong, Yan, Benedict, Chu, Justin Jang Hann, Chow, Vincent TK, Alonso, Sylvie
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Language: English
• Published: FRONTIERS MEDIA SA 2022
• Subjects: Science & Technology; Life Sciences & Biomedicine; Microbiology; foot and mouth disease (HFMD); enterovirus A-71; SCARB2; VP2 EF loop; neurovirulence; MOUTH-DISEASE; CONTROL OUTBREAKS; C4 STRAIN; HAND; FOOT; INFECTION; EPIDEMIOLOGY; ADAPTATION; ATTACHMENT; MUTATIONS
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/235422
• Institution: National University of Singapore

10.3389/fmicb.2022.821976