iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer

10.1038/s41586-023-06713-1

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Main Authors: Park, Dong Shin, Kozaki, Tatsuya, Tiwari, Satish Kumar, Moreira, Marco, Khalilnezhad, Ahad, Torta, Federico, Olivie, Nicolas, Thiam, Chung Hwee, Liani, Oniko, Silvin, Aymeric, Phoo, Wint Wint, Gao, Liang, Triebl, Alexander, Tham, Wai Kin, Goncalves, Leticia, Kong, Wan Ting, Raman, Sethi, Zhang, Xiao Meng, Dunsmore, Garett, Dutertre, Charles Antoine, Lee, Salanne, Ong, Jia Min, Balachander, Akhila, Khalilnezhad, Shabnam, Lum, Josephine, Duan, Kaibo, Lim, Ze Ming, Tan, Leonard, Low, Ivy, Utami, Kagistia Hana, Yeo, Xin Yi, Di Tommaso, Sylvaine, Dupuy, Jean-William, Varga, Balazs, Karadottir, Ragnhildur Thora, Madathummal, Mufeeda Changaramvally, Bonne, Isabelle, Malleret, Benoit, Binte, Zainab Yasin, Da, Ngan Wei, Tan, Yingrou, Wong, Wei Jie, Zhang, Jinqiu, Chen, Jinmiao, Sobota, Radoslaw M, Howland, Shanshan W, Ng, Lai Guan, Saltel, Frederic, Castel, David, Grill, Jacques, Minard, Veronique, Albani, Salvatore, Chan, Jerry KY, Thion, Morgane Sonia, Jung, Sang Yong, Wenk, Markus R, Pouladi, Mahmoud A, Pasqualini, Claudia, Angeli, Veronique, Cexus, Olivier NF, Ginhoux, Florent
Other Authors: MICROBIOLOGY AND IMMUNOLOGY
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Language:English
Published: NATURE PORTFOLIO 2024
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/247854
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spelling sg-nus-scholar.10635-2478542024-11-15T09:13:24Z iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer Park, Dong Shin Kozaki, Tatsuya Tiwari, Satish Kumar Moreira, Marco Khalilnezhad, Ahad Torta, Federico Olivie, Nicolas Thiam, Chung Hwee Liani, Oniko Silvin, Aymeric Phoo, Wint Wint Gao, Liang Triebl, Alexander Tham, Wai Kin Goncalves, Leticia Kong, Wan Ting Raman, Sethi Zhang, Xiao Meng Dunsmore, Garett Dutertre, Charles Antoine Lee, Salanne Ong, Jia Min Balachander, Akhila Khalilnezhad, Shabnam Lum, Josephine Duan, Kaibo Lim, Ze Ming Tan, Leonard Low, Ivy Utami, Kagistia Hana Yeo, Xin Yi Di Tommaso, Sylvaine Dupuy, Jean-William Varga, Balazs Karadottir, Ragnhildur Thora Madathummal, Mufeeda Changaramvally Bonne, Isabelle Malleret, Benoit Binte, Zainab Yasin Da, Ngan Wei Tan, Yingrou Wong, Wei Jie Zhang, Jinqiu Chen, Jinmiao Sobota, Radoslaw M Howland, Shanshan W Ng, Lai Guan Saltel, Frederic Castel, David Grill, Jacques Minard, Veronique Albani, Salvatore Chan, Jerry KY Thion, Morgane Sonia Jung, Sang Yong Wenk, Markus R Pouladi, Mahmoud A Pasqualini, Claudia Angeli, Veronique Cexus, Olivier NF Ginhoux, Florent MICROBIOLOGY AND IMMUNOLOGY LIFE SCIENCES INSTITUTE DUKE-NUS MEDICAL SCHOOL BIOCHEMISTRY Assoc Prof Veronique Angeli Science & Technology Multidisciplinary Sciences Science & Technology - Other Topics PLURIPOTENT STEM-CELLS CEREBRAL ORGANOIDS ADULT MICROGLIA IN-VIVO NEUROGENESIS NEURONS DIFFERENTIATION ASTROCYTES FEATURES CORTEX 10.1038/s41586-023-06713-1 NATURE 623 7986 2024-04-12T07:51:09Z 2024-04-12T07:51:09Z 2023-11-09 2024-04-11T14:26:34Z Article Park, Dong Shin, Kozaki, Tatsuya, Tiwari, Satish Kumar, Moreira, Marco, Khalilnezhad, Ahad, Torta, Federico, Olivie, Nicolas, Thiam, Chung Hwee, Liani, Oniko, Silvin, Aymeric, Phoo, Wint Wint, Gao, Liang, Triebl, Alexander, Tham, Wai Kin, Goncalves, Leticia, Kong, Wan Ting, Raman, Sethi, Zhang, Xiao Meng, Dunsmore, Garett, Dutertre, Charles Antoine, Lee, Salanne, Ong, Jia Min, Balachander, Akhila, Khalilnezhad, Shabnam, Lum, Josephine, Duan, Kaibo, Lim, Ze Ming, Tan, Leonard, Low, Ivy, Utami, Kagistia Hana, Yeo, Xin Yi, Di Tommaso, Sylvaine, Dupuy, Jean-William, Varga, Balazs, Karadottir, Ragnhildur Thora, Madathummal, Mufeeda Changaramvally, Bonne, Isabelle, Malleret, Benoit, Binte, Zainab Yasin, Da, Ngan Wei, Tan, Yingrou, Wong, Wei Jie, Zhang, Jinqiu, Chen, Jinmiao, Sobota, Radoslaw M, Howland, Shanshan W, Ng, Lai Guan, Saltel, Frederic, Castel, David, Grill, Jacques, Minard, Veronique, Albani, Salvatore, Chan, Jerry KY, Thion, Morgane Sonia, Jung, Sang Yong, Wenk, Markus R, Pouladi, Mahmoud A, Pasqualini, Claudia, Angeli, Veronique, Cexus, Olivier NF, Ginhoux, Florent (2023-11-09). iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer. NATURE 623 (7986). ScholarBank@NUS Repository. https://doi.org/10.1038/s41586-023-06713-1 1476-4687 0028-0836 https://scholarbank.nus.edu.sg/handle/10635/247854 en NATURE PORTFOLIO Elements
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
language English
topic Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
PLURIPOTENT STEM-CELLS
CEREBRAL ORGANOIDS
ADULT MICROGLIA
IN-VIVO
NEUROGENESIS
NEURONS
DIFFERENTIATION
ASTROCYTES
FEATURES
CORTEX
spellingShingle Science & Technology
Multidisciplinary Sciences
Science & Technology - Other Topics
PLURIPOTENT STEM-CELLS
CEREBRAL ORGANOIDS
ADULT MICROGLIA
IN-VIVO
NEUROGENESIS
NEURONS
DIFFERENTIATION
ASTROCYTES
FEATURES
CORTEX
Park, Dong Shin
Kozaki, Tatsuya
Tiwari, Satish Kumar
Moreira, Marco
Khalilnezhad, Ahad
Torta, Federico
Olivie, Nicolas
Thiam, Chung Hwee
Liani, Oniko
Silvin, Aymeric
Phoo, Wint Wint
Gao, Liang
Triebl, Alexander
Tham, Wai Kin
Goncalves, Leticia
Kong, Wan Ting
Raman, Sethi
Zhang, Xiao Meng
Dunsmore, Garett
Dutertre, Charles Antoine
Lee, Salanne
Ong, Jia Min
Balachander, Akhila
Khalilnezhad, Shabnam
Lum, Josephine
Duan, Kaibo
Lim, Ze Ming
Tan, Leonard
Low, Ivy
Utami, Kagistia Hana
Yeo, Xin Yi
Di Tommaso, Sylvaine
Dupuy, Jean-William
Varga, Balazs
Karadottir, Ragnhildur Thora
Madathummal, Mufeeda Changaramvally
Bonne, Isabelle
Malleret, Benoit
Binte, Zainab Yasin
Da, Ngan Wei
Tan, Yingrou
Wong, Wei Jie
Zhang, Jinqiu
Chen, Jinmiao
Sobota, Radoslaw M
Howland, Shanshan W
Ng, Lai Guan
Saltel, Frederic
Castel, David
Grill, Jacques
Minard, Veronique
Albani, Salvatore
Chan, Jerry KY
Thion, Morgane Sonia
Jung, Sang Yong
Wenk, Markus R
Pouladi, Mahmoud A
Pasqualini, Claudia
Angeli, Veronique
Cexus, Olivier NF
Ginhoux, Florent
iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer
description 10.1038/s41586-023-06713-1
author2 MICROBIOLOGY AND IMMUNOLOGY
author_facet MICROBIOLOGY AND IMMUNOLOGY
Park, Dong Shin
Kozaki, Tatsuya
Tiwari, Satish Kumar
Moreira, Marco
Khalilnezhad, Ahad
Torta, Federico
Olivie, Nicolas
Thiam, Chung Hwee
Liani, Oniko
Silvin, Aymeric
Phoo, Wint Wint
Gao, Liang
Triebl, Alexander
Tham, Wai Kin
Goncalves, Leticia
Kong, Wan Ting
Raman, Sethi
Zhang, Xiao Meng
Dunsmore, Garett
Dutertre, Charles Antoine
Lee, Salanne
Ong, Jia Min
Balachander, Akhila
Khalilnezhad, Shabnam
Lum, Josephine
Duan, Kaibo
Lim, Ze Ming
Tan, Leonard
Low, Ivy
Utami, Kagistia Hana
Yeo, Xin Yi
Di Tommaso, Sylvaine
Dupuy, Jean-William
Varga, Balazs
Karadottir, Ragnhildur Thora
Madathummal, Mufeeda Changaramvally
Bonne, Isabelle
Malleret, Benoit
Binte, Zainab Yasin
Da, Ngan Wei
Tan, Yingrou
Wong, Wei Jie
Zhang, Jinqiu
Chen, Jinmiao
Sobota, Radoslaw M
Howland, Shanshan W
Ng, Lai Guan
Saltel, Frederic
Castel, David
Grill, Jacques
Minard, Veronique
Albani, Salvatore
Chan, Jerry KY
Thion, Morgane Sonia
Jung, Sang Yong
Wenk, Markus R
Pouladi, Mahmoud A
Pasqualini, Claudia
Angeli, Veronique
Cexus, Olivier NF
Ginhoux, Florent
format Article
author Park, Dong Shin
Kozaki, Tatsuya
Tiwari, Satish Kumar
Moreira, Marco
Khalilnezhad, Ahad
Torta, Federico
Olivie, Nicolas
Thiam, Chung Hwee
Liani, Oniko
Silvin, Aymeric
Phoo, Wint Wint
Gao, Liang
Triebl, Alexander
Tham, Wai Kin
Goncalves, Leticia
Kong, Wan Ting
Raman, Sethi
Zhang, Xiao Meng
Dunsmore, Garett
Dutertre, Charles Antoine
Lee, Salanne
Ong, Jia Min
Balachander, Akhila
Khalilnezhad, Shabnam
Lum, Josephine
Duan, Kaibo
Lim, Ze Ming
Tan, Leonard
Low, Ivy
Utami, Kagistia Hana
Yeo, Xin Yi
Di Tommaso, Sylvaine
Dupuy, Jean-William
Varga, Balazs
Karadottir, Ragnhildur Thora
Madathummal, Mufeeda Changaramvally
Bonne, Isabelle
Malleret, Benoit
Binte, Zainab Yasin
Da, Ngan Wei
Tan, Yingrou
Wong, Wei Jie
Zhang, Jinqiu
Chen, Jinmiao
Sobota, Radoslaw M
Howland, Shanshan W
Ng, Lai Guan
Saltel, Frederic
Castel, David
Grill, Jacques
Minard, Veronique
Albani, Salvatore
Chan, Jerry KY
Thion, Morgane Sonia
Jung, Sang Yong
Wenk, Markus R
Pouladi, Mahmoud A
Pasqualini, Claudia
Angeli, Veronique
Cexus, Olivier NF
Ginhoux, Florent
author_sort Park, Dong Shin
title iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer
title_short iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer
title_full iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer
title_fullStr iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer
title_full_unstemmed iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer
title_sort ips-cell-derived microglia promote brain organoid maturation via cholesterol transfer
publisher NATURE PORTFOLIO
publishDate 2024
url https://scholarbank.nus.edu.sg/handle/10635/247854
_version_ 1821198899144032256