Structural and Functional Analysis of Multi-interface Domains

• Main Authors: ZHAO, Liang, HOI, Steven C. H., WONG, Limsoon, HAMP, Tobias, LI, Jinyan
• Format: text
• Language: English
• Published: Institutional Knowledge at Singapore Management University 2012
• Subjects: algorithm; beta chain; binding site; catalysis; protein analysis; protein binding; protein database; Computer Sciences; Databases and Information Systems
• Online Access: https://ink.library.smu.edu.sg/sis_research/2297; https://ink.library.smu.edu.sg/context/sis_research/article/3297/viewcontent/HoiS2012journal.pone.0050821.pdf
• Institution: Singapore Management University

A multi-interface domain is a domain that can shape multiple and distinctive binding sites to contact with many other domains, forming a hub in domain-domain interaction networks. The functions played by the multiple interfaces are usually different, but there is no strict bijection between the func...