Mitochondrial calcium uniporter blocker prevents cardiac mitochondrial dysfunction induced by iron overload in thalassemic mice

Mitochondrial calcium uniporter blocker prevents cardiac mitochondrial dysfunction induced by iron overload in thalassemic mice

Iron-overload induced cardiomyopathy is a major cause of morbidity and mortality in thalassemic patients. Previous studies suggest that cardiac mitochondrial dysfunction may be involved in the pathogenesis of cardiomyopathy in thalassemia. We tested the hypothesis that iron overload causes dysfuncti...

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書目詳細資料
Main Authors:	Kumfu S., Chattipakorn S., Fucharoen S., Chattipakorn N.
格式:	Article
語言:	English
出版:	2014
在線閱讀:	http://www.scopus.com/inward/record.url?eid=2-s2.0-84865050953&partnerID=40&md5=743664c2f614cb60e10b419b5b55641b http://www.ncbi.nlm.nih.gov/pubmed/22910858 http://cmuir.cmu.ac.th/handle/6653943832/1138
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