Inhibition of P-glycoprotein function and expression by kaempferol and quercetin

The 170 kDa plasma membrane P-glycoprotein (Pgp) causes the efflux of chemotherapeutic drugs from cells and is believed to be an important mechanism in multidrug resistance (MDR) in human cancer. This study demonstrates that some putative flavonoids, i.e., flavonols (quercetin and kaempferol) and is...

Full description

Saved in:
Bibliographic Details
Main Authors: Limtrakul P., Khantamat O., Pintha K.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-16244371036&partnerID=40&md5=7dc5d46f53a57f83554f3812c0756764
http://www.ncbi.nlm.nih.gov/pubmed/15828450
http://cmuir.cmu.ac.th/handle/6653943832/1954
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Chiang Mai University
Language: English