Inhibition of P-glycoprotein function and expression by kaempferol and quercetin
The 170 kDa plasma membrane P-glycoprotein (Pgp) causes the efflux of chemotherapeutic drugs from cells and is believed to be an important mechanism in multidrug resistance (MDR) in human cancer. This study demonstrates that some putative flavonoids, i.e., flavonols (quercetin and kaempferol) and is...
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Main Authors: | Limtrakul P., Khantamat O., Pintha K. |
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Format: | Article |
Language: | English |
Published: |
2014
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Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-16244371036&partnerID=40&md5=7dc5d46f53a57f83554f3812c0756764 http://www.ncbi.nlm.nih.gov/pubmed/15828450 http://cmuir.cmu.ac.th/handle/6653943832/1954 |
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Institution: | Chiang Mai University |
Language: | English |
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