Inhibition of P-glycoprotein function and expression by kaempferol and quercetin

The 170 kDa plasma membrane P-glycoprotein (Pgp) causes the efflux of chemotherapeutic drugs from cells and is believed to be an important mechanism in multidrug resistance (MDR) in human cancer. This study demonstrates that some putative flavonoids, i.e., flavonols (quercetin and kaempferol) and is...

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Bibliographic Details
Main Authors: Limtrakul P., Khantamat O., Pintha K.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-16244371036&partnerID=40&md5=7dc5d46f53a57f83554f3812c0756764
http://www.ncbi.nlm.nih.gov/pubmed/15828450
http://cmuir.cmu.ac.th/handle/6653943832/1954
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Institution: Chiang Mai University
Language: English

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