The influence of pH on the G-quadruplex binding selectivity of perylene derivatives
Three new perylene derivatives with branched ionizable side chains were synthesized, and their G-quadruplex binding specificities were compared by spectroscopic and electrophoretic analysis with two well-studied G-quadruplex ligands: PIPER and TmPyP4. The value of pH and consequent charge formation...
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th-cmuir.6653943832-20622014-08-30T02:00:26Z The influence of pH on the G-quadruplex binding selectivity of perylene derivatives Tuntiwechapikul W. Taka T. Bethencourt M. Makonkawkeyoon L. Randall Lee T. Three new perylene derivatives with branched ionizable side chains were synthesized, and their G-quadruplex binding specificities were compared by spectroscopic and electrophoretic analysis with two well-studied G-quadruplex ligands: PIPER and TmPyP4. The value of pH and consequent charge formation and self-aggregation of these perylene derivatives influences not only the type of G-quadruplex formation, but also the G-quadruplex binding selectivity. © 2006 Elsevier Ltd. All rights reserved. 2014-08-30T02:00:26Z 2014-08-30T02:00:26Z 2006 Article 0960894X 10.1016/j.bmcl.2006.04.078 16713263 BMCLE http://www.scopus.com/inward/record.url?eid=2-s2.0-33745141952&partnerID=40&md5=16a2df1db67a778619993a7da18008a2 http://www.ncbi.nlm.nih.gov/pubmed/16713263 http://cmuir.cmu.ac.th/handle/6653943832/2062 English |
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Three new perylene derivatives with branched ionizable side chains were synthesized, and their G-quadruplex binding specificities were compared by spectroscopic and electrophoretic analysis with two well-studied G-quadruplex ligands: PIPER and TmPyP4. The value of pH and consequent charge formation and self-aggregation of these perylene derivatives influences not only the type of G-quadruplex formation, but also the G-quadruplex binding selectivity. © 2006 Elsevier Ltd. All rights reserved. |
| format |
Article |
| author |
Tuntiwechapikul W. Taka T. Bethencourt M. Makonkawkeyoon L. Randall Lee T. |
| spellingShingle |
Tuntiwechapikul W. Taka T. Bethencourt M. Makonkawkeyoon L. Randall Lee T. The influence of pH on the G-quadruplex binding selectivity of perylene derivatives |
| author_facet |
Tuntiwechapikul W. Taka T. Bethencourt M. Makonkawkeyoon L. Randall Lee T. |
| author_sort |
Tuntiwechapikul W. |
| title |
The influence of pH on the G-quadruplex binding selectivity of perylene derivatives |
| title_short |
The influence of pH on the G-quadruplex binding selectivity of perylene derivatives |
| title_full |
The influence of pH on the G-quadruplex binding selectivity of perylene derivatives |
| title_fullStr |
The influence of pH on the G-quadruplex binding selectivity of perylene derivatives |
| title_full_unstemmed |
The influence of pH on the G-quadruplex binding selectivity of perylene derivatives |
| title_sort |
influence of ph on the g-quadruplex binding selectivity of perylene derivatives |
| publishDate |
2014 |
| url |
http://www.scopus.com/inward/record.url?eid=2-s2.0-33745141952&partnerID=40&md5=16a2df1db67a778619993a7da18008a2 http://www.ncbi.nlm.nih.gov/pubmed/16713263 http://cmuir.cmu.ac.th/handle/6653943832/2062 |
| _version_ |
1681419787561861120 |