Production of monoclonal antibodies to P-glycoprotein: Its application in detection of soluble and surface P-glycoprotein of leukemia patients

Production of monoclonal antibodies to P-glycoprotein: Its application in detection of soluble and surface P-glycoprotein of leukemia patients

Multidrug resistance (MDR) in leukemia is commonly associated with the expression of a transmembrane protein, P-glycoprotein (P-gp). In this study, two monoclonal antibodies (mAbs) specific for the extracellular domain of P-gp were generated. By employing the generated mAbs, a two-color lysed whole...

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Bibliographic Details
Main Authors: Chiampanichayakul S., Anuchapreeda S., Chruewkamlow N., Mahasongkram K., Thanaratanakorn P., Kasinrerk W.
Format: Article
Language:English
Published: 2014
Online Access:http://www.scopus.com/inward/record.url?eid=2-s2.0-77956896273&partnerID=40&md5=7a0918b59903cbbded5b676b0e358f15
http://www.ncbi.nlm.nih.gov/pubmed/20740331
http://cmuir.cmu.ac.th/handle/6653943832/2545
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Institution: Chiang Mai University
Language: English

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http://www.scopus.com/inward/record.url?eid=2-s2.0-77956896273&partnerID=40&md5=7a0918b59903cbbded5b676b0e358f15
http://www.ncbi.nlm.nih.gov/pubmed/20740331
http://cmuir.cmu.ac.th/handle/6653943832/2545

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