Production of monoclonal antibodies to P-glycoprotein: Its application in detection of soluble and surface P-glycoprotein of leukemia patients
Multidrug resistance (MDR) in leukemia is commonly associated with the expression of a transmembrane protein, P-glycoprotein (P-gp). In this study, two monoclonal antibodies (mAbs) specific for the extracellular domain of P-gp were generated. By employing the generated mAbs, a two-color lysed whole...
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Main Authors: | Chiampanichayakul S., Anuchapreeda S., Chruewkamlow N., Mahasongkram K., Thanaratanakorn P., Kasinrerk W. |
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Format: | Article |
Language: | English |
Published: |
2014
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Online Access: | http://www.scopus.com/inward/record.url?eid=2-s2.0-77956896273&partnerID=40&md5=7a0918b59903cbbded5b676b0e358f15 http://www.ncbi.nlm.nih.gov/pubmed/20740331 http://cmuir.cmu.ac.th/handle/6653943832/2545 |
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Institution: | Chiang Mai University |
Language: | English |
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