Functional importance of the Gly cluster in transmembrane helix 2 of the Bordetella pertussis CyaA-hemolysin: Implications for toxin oligomerization and pore formation

© 2015 Published by Elsevier Ltd. Adenylate cyclase-hemolysin (CyaA) is a major virulence factor of Bordetella pertussis causing whooping cough in humans. We previously showed that two transmembrane helices (α2 and α3) in the hemolysin domain (CyaA-Hly) are crucially involved in hemolytic activity....

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Main Authors: Sirikran Juntapremjit, Niramon Thamwiriyasati, Chattip Kurehong, Panchika Prangkio, Lalida Shank, Busaba Powthongchin, Chanan Angsuthanasombat
Format: Journal
Published: 2018
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Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84941985118&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/44112
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Institution: Chiang Mai University

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