A dihydroxy-pentamethoxyflavone from Gardenia obtusifolia suppresses proliferation and promotes apoptosis of tumor cells through modulation of multiple cell signaling pathways
We sought to determine the molecular basis for the anticancer activities of 5,3′-dihydroxy-3,6,7,8,4′-penta-methoxyflavone (DH-PMF), isolated from Gardenia obtusifolia traditionally used in Thailand for a variety of ailments. As little as 1 μM DH-PMF inhibited the proliferation of prostate, colon, k...
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Main Authors: | Kanokkarn Phromnoi, Simone Reuter, Bokyung Sung, Pornngarm Limtrakul, Bharat B. Aggarwal |
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Format: | Journal |
Published: |
2018
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Subjects: | |
Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77958572996&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/50542 |
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Institution: | Chiang Mai University |
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