Zinc finger protein designed to target 2-long terminal repeat junctions interferes with human immunodeficiency virus integration

Zinc finger protein designed to target 2-long terminal repeat junctions interferes with human immunodeficiency virus integration

Integration of the human immunodeficiency virus type 1 (HIV-1) genome into the host chromosome is a vital step in the HIV life cycle. The highly conserved cytosine-adenine (CA) dinucleotide sequence immediately upstream of the cleavage site is crucial for integrase (IN) activity. As this viral enzym...

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Bibliographic Details
Main Authors: Supachai Sakkhachornphop, Carlos F. Barbas, Rassamee Keawvichit, Kanlaya Wongworapat, Chatchai Tayapiwatana
Format: Journal
Published: 2018
Subjects:
Biochemistry, Genetics and Molecular Biology
Online Access:https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84866325679&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51361
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Institution: Chiang Mai University

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https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84866325679&origin=inward
http://cmuir.cmu.ac.th/jspui/handle/6653943832/51361

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