Zinc finger protein designed to target 2-long terminal repeat junctions interferes with human immunodeficiency virus integration
Integration of the human immunodeficiency virus type 1 (HIV-1) genome into the host chromosome is a vital step in the HIV life cycle. The highly conserved cytosine-adenine (CA) dinucleotide sequence immediately upstream of the cleavage site is crucial for integrase (IN) activity. As this viral enzym...
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Main Authors: | Supachai Sakkhachornphop, Carlos F. Barbas, Rassamee Keawvichit, Kanlaya Wongworapat, Chatchai Tayapiwatana |
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Format: | Journal |
Published: |
2018
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Subjects: | |
Online Access: | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84866325679&origin=inward http://cmuir.cmu.ac.th/jspui/handle/6653943832/51361 |
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Institution: | Chiang Mai University |
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