Epigallocatechin-3-gallate and epicatechin-3-gallate from green tea decrease plasma non-transferrin bound iron and erythrocyte oxidative stress

• Main Authors: C. Thephinlap, S. Ounjaijean, U. Khansuwan, S. Fucharoen, J. B. Porter, S. Srichairatanakool
• 格式: 雜誌
• 出版: 2018
• 主題: Pharmacology, Toxicology and Pharmaceutics
• 在線閱讀: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=34248657988&origin=inward; http://cmuir.cmu.ac.th/jspui/handle/6653943832/61377
• 機構: Chiang Mai University

β-Thalassemia patients suffer from secondary iron overload caused by increased iron absorption and multiple blood transfusions. Excessive iron catalyzes free-radical formation, causing oxidative tissue damage. Non-transferrin bound iron (NTBI) detected in thalassemic plasma is highly toxic and chela...