Geographical distribution of selected and putatively neutral SNPs in Southeast Asian malaria parasites

• Main Authors: Tim J.C. Anderson, Shalini Nair, Dan Sudimack, Jeff T. Williams, Mayfong Mayxay, Paul N. Newton, Jean Paul Guthmann, Frank M. Smithuis, Tran Tinh Hien, Ingrid V.F. Van Den Broek, Nicholas J. White, François Nosten
• Other Authors: Texas Biomedical Research Institute
• Format: Article
• Published: 2018
• Subjects: Agricultural and Biological Sciences; Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/16186
• Institution: Mahidol University

Loci targeted by directional selection are expected to show elevated geographical population structure relative to neutral loci, and a flurry of recent papers have used this rationale to search for genome regions involved in adaptation. Studies of functional mutations that are known to be under sele...