Homology building as a means to define antigenic epitopes on dihydrofolate reductase (DHFR) from Plasmodium falciparum

Homology building as a means to define antigenic epitopes on dihydrofolate reductase (DHFR) from Plasmodium falciparum

Background: The aim of this study was to develop site-specific antibodies as a tool to capture Plasmodium falciparum-dihydrofolate reductase (Pf-DHFR) from blood samples from P. falciparum infected individuals in order to detect, in a sandwich ELISA, structural alterations due to point mutations in...

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Bibliographic Details
Main Authors: Michael Alifrangis, Inge T. Christensen, Flemming S. Jørgensen, Anita M. Rønn, Jimmy E. Weng, Ming Chen, Ib C. Bygbjerg, Worachart Sirawaraporn, Yaseelan Palarasah, Claus Koch
Other Authors: Kobenhavns Universitet
Format: Article
Published: 2018
Subjects:
Immunology and Microbiology
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/21374
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/21374

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