Homology building as a means to define antigenic epitopes on dihydrofolate reductase (DHFR) from Plasmodium falciparum
Background: The aim of this study was to develop site-specific antibodies as a tool to capture Plasmodium falciparum-dihydrofolate reductase (Pf-DHFR) from blood samples from P. falciparum infected individuals in order to detect, in a sandwich ELISA, structural alterations due to point mutations in...
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Main Authors: | Michael Alifrangis, Inge T. Christensen, Flemming S. Jørgensen, Anita M. Rønn, Jimmy E. Weng, Ming Chen, Ib C. Bygbjerg, Worachart Sirawaraporn, Yaseelan Palarasah, Claus Koch |
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Other Authors: | Kobenhavns Universitet |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/21374 |
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Institution: | Mahidol University |
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