Effect of salt forms and molecular weight of chitosans on in vitro permeability enhancement in intestinal epithelial cells (Caco-2)

• Main Authors: Praneet Opanasopit, Polawan Aumklad, Jarija Kowapradit, Tanasait Ngawhiranpat, Auayporn Apirakaramwong, Theerasak Rojanarata, Satit Puttipipatkhachorn
• Other Authors: Silpakorn University
• Format: Article
• Published: 2018
• Subjects: Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/25094
• Institution: Mahidol University

The purpose of this study was to investigate the effect of molecular weight (MW) and salt forms of chitosans (aspartate; CS A, glutamate; CS G, lactate; CS L and hydrochloride, CS HCl) on the transepithelial electrical resistance (TEER) and permeability of Caco-2 cells monolayer, using fluorescein i...