Mitochondrial complex i deficiency increases protein acetylation and accelerates heart failure
Mitochondrial respiratory dysfunction is linked to the pathogenesis of multiple diseases, including heart failure, but the specific mechanisms for this link remain largely elusive. We modeled the impairment of mitochondrial respiration by the inactivation of the Ndufs4 gene, a protein critical for c...
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Main Authors: | Georgios Karamanlidis, Chi Fung Lee, Lorena Garcia-Menendez, Stephen C. Kolwicz, Wichit Suthammarak, Guohua Gong, Margaret M. Sedensky, Philip G. Morgan, Wang Wang, Rong Tian |
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Other Authors: | University of Washington, Seattle |
Format: | Article |
Published: |
2018
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/31245 |
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Institution: | Mahidol University |
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