Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania.

Artemether-lumefantrine is currently first-line therapy of Plasmodium falciparum malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa. Genotyping confirmed recrudescence and suggested reduced se...

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Main Authors:	Färnert, Anna, Ursing, Johan, Tolfvenstam, Thomas, Rono, Josea, Karlsson, Lillemor, Sparrelid, Elda, Lindegårdh, Niklas
Other Authors:	anna.farnert@ki.se
Language:	English
Published:	2014
Subjects:	Artemisnin Lumefantrine Malaria non-immune P. falciparum Open Access article
Online Access:	https://repository.li.mahidol.ac.th/handle/123456789/666
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Institution:	Mahidol University
Language:	English

id	th-mahidol.666
record_format	dspace
spelling	th-mahidol.6662023-03-31T00:34:21Z Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania. Färnert, Anna Ursing, Johan Tolfvenstam, Thomas Rono, Josea Karlsson, Lillemor Sparrelid, Elda Lindegårdh, Niklas anna.farnert@ki.se Mahidol University. Faculty of Tropical Medicine. Mahidol-Oxford Tropical Medicine Research Unit. Artemisnin Lumefantrine Malaria non-immune P. falciparum Open Access article Artemether-lumefantrine is currently first-line therapy of Plasmodium falciparum malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa. Genotyping confirmed recrudescence and suggested reduced sensitivity. Potential sub-optimal effect of artemether-lumefantrine highlights the need to follow non-immune individuals the weeks after treatment. 2014-06-30T07:18:24Z 2016-09-21T03:24:29Z 2014-06-30T07:18:24Z 2016-09-21T03:24:29Z 2012 2014-06-25 2012-05-25 Färnert A, Ursing J, Tolfvenstam T, Rono J, Karlsson L, Sparrelid E, et al. Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania. Malar J. 2012 May 25;11:176. 10.1186/1475-2875-11-176. 1475-2875 (electronic) 1475-2875 (Linking) https://repository.li.mahidol.ac.th/handle/123456789/666 eng Mahidol University BioMed Central application/pdf
institution	Mahidol University
building	Mahidol University Library
continent	Asia
country	Thailand Thailand
content_provider	Mahidol University Library
collection	Mahidol University Institutional Repository
language	English
topic	Artemisnin Lumefantrine Malaria non-immune P. falciparum Open Access article
spellingShingle	Artemisnin Lumefantrine Malaria non-immune P. falciparum Open Access article Färnert, Anna Ursing, Johan Tolfvenstam, Thomas Rono, Josea Karlsson, Lillemor Sparrelid, Elda Lindegårdh, Niklas Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania.
description	Artemether-lumefantrine is currently first-line therapy of Plasmodium falciparum malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa. Genotyping confirmed recrudescence and suggested reduced sensitivity. Potential sub-optimal effect of artemether-lumefantrine highlights the need to follow non-immune individuals the weeks after treatment.
author2	anna.farnert@ki.se
author_facet	anna.farnert@ki.se Färnert, Anna Ursing, Johan Tolfvenstam, Thomas Rono, Josea Karlsson, Lillemor Sparrelid, Elda Lindegårdh, Niklas
author	Färnert, Anna Ursing, Johan Tolfvenstam, Thomas Rono, Josea Karlsson, Lillemor Sparrelid, Elda Lindegårdh, Niklas
author_sort	Färnert, Anna
title	Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania.
title_short	Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania.
title_full	Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania.
title_fullStr	Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania.
title_full_unstemmed	Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania.
title_sort	artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with plasmodium falciparum malaria after returning from tanzania.
publishDate	2014
url	https://repository.li.mahidol.ac.th/handle/123456789/666
_version_	1763497510404358144

Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania.

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