Artemether-lumefantrine treatment failure despite adequate lumefantrine day 7 concentration in a traveller with Plasmodium falciparum malaria after returning from Tanzania.

• Main Authors: Färnert, Anna, Ursing, Johan, Tolfvenstam, Thomas, Rono, Josea, Karlsson, Lillemor, Sparrelid, Elda, Lindegårdh, Niklas
• Other Authors: [e-mail]
• Language: English
• Published: 2014
• Subjects: Artemisnin; Lumefantrine; Malaria; non-immune; P. falciparum; Open Access article
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/666
• Institution: Mahidol University

Artemether-lumefantrine is currently first-line therapy of Plasmodium falciparum malaria in many countries. This report describes a treatment failure despite adequate drug concentrations in a traveller returning from sub-Saharan Africa. Genotyping confirmed recrudescence and suggested reduced se...