Intracellular expression of granzymes A, B, K and M in blood lymphocyte subsets of critically ill patients with or without sepsis

by M. Isabel García-Laorden, Arie J. Hoogendijk, Maryse A. Wiewel, Lonneke A. van Vught, Marcus J. Schultz, Niels Bovenschen, Alex F. de Vos, Tom van der Poll
Published 2022

Therapeutic administration of a monoclonal anti-IL-1β antibody protects against experimental melioidosis

by Tassili A.F. Weehuizen, Jacqueline M. Lankelma, Hanna K. De Jong, Onno J. De Boer, Joris J.T.H. Roelofs, Nicholas P. Day, Hermann Gram, Alex F. De Vos, W. Joost Wiersinga
Published 2018

Thrombocytopenia Impairs Host Defense Against Burkholderia pseudomallei (Melioidosis)

by Emma Birnie, Theodora A.M. Claushuis, Gavin C.K.W. Koh, Direk Limmathurotsakul, Nicholas P.J. Day, Joris J.T.H. Roelofs, Jerry Ware, Baidong Hou, Alex F. De Vos, Tom Van Der Poll, Cornelis Van't Veer, W. Joost Wiersinga
Published 2020

Urokinase receptor is necessary for bacterial defense against pneumonia-derived septic melioidosis by facilitating phagocytosis

by W. Joost Wiersinga, Liesbeth M. Kager, Joppe W.R. Hovius, Gerritje J.W. Van Der Windt, Alex F. De Vos, Joost C.M. Meijers, Joris J. Roelofs, Arjen Dondorp, Marcel Levi, Nicholas P. Day, Sharon J. Peacock, Tom Van Der Poll
Published 2018

Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis)

by W. Joost Wiersinga, Catharina W. Wieland, Mark C. Dessing, Narisara Chantratita, Allen C. Cheng, Direk Limmathurotsakul, Wirongrong Chierakul, Masja Leendertse, Sandrine Florquin, Alex F. De Vos, Nicholas White, Arjen M. Dondorp, Nicholas P. Day, Sharon J. Peacock, Tom Van Der Poll
Published 2018

HIVEP1 Is a Negative Regulator of NF-κB That Inhibits Systemic Inflammation in Sepsis

by Hisatake Matsumoto, Brendon P. Scicluna, Kin Ki Jim, Fahimeh Falahi, Wanhai Qin, Berke Gürkan, Erik Malmström, Mariska T. Meijer, Joe M. Butler, Hina N. Khan, Tsuyoshi Takagi, Shunsuke Ishii, Marcus J. Schultz, Diederik van de Beek, Alex F. de Vos, Cornelis van ‘t Veer, Tom van der Poll
Published 2022

Expression and Function of S100A8/A9 (Calprotectin) in Human Typhoid Fever and the Murine Salmonella Model

by Hanna K. De Jong, Ahmed Achouiti, Gavin C.K.W. Koh, Christopher M. Parry, Stephen Baker, Mohammed Abul Faiz, Jaap T. van Dissel, Albert M. Vollaard, Ester M.M. van Leeuwen, Joris J.T.H. Roelofs, Alex F. de Vos, Johannes Roth, Tom van der Poll, Thomas Vogl, Willem Joost Wiersinga
Published 2018

Increased intra- and extracellular granzyme expression in patients with tuberculosis

by M. Isabel Garcia-Laorden, Dana C. Blok, Liesbeth M. Kager, Arie J. Hoogendijk, Gerard J. Van Mierlo, Ivar O. Lede, Wahid Rahman, Rumana Afroz, Aniruddha Ghose, Caroline E. Visser, Abu Shahed Md Zahed, Md Anwar Husain, Khan Mashrequl Alam, Pravat Chandra Barua, Mahtabuddin Hassan, Ahmed Hossain, Md Abu Tayab, Nick Day, Arjen M. Dondorp, Alex F. De Vos, Tom Van Der Poll
Published 2018

Expression of inhibitory regulators of innate immunity in patients with active tuberculosis

by Dana C. Blok, Liesbeth M. Kager, Arie J. Hoogendijk, Ivar O. Lede, Wahid Rahman, Rumana Afroz, Paul Bresser, Jaring S. van der Zee, Aniruddha Ghose, Caroline E. Visser, Menno D. de Jong, Abu Shahed Md Zahed, Md Anwar Husain, Khan Mashrequl Alam, Pravat Chandra Barua, Mahtabuddin Hassan, Ahmed Hossain, Md Abu Tayab, Rene Lutter, Nick Day, Arjen M. Dondorp, Alex F. de Vos, Cornelis van 't Veer, Tom van der Poll
Published 2018