HMGB1 as a therapeutic target in spinal cord injury: A hypothesis for novel therapy development (Review)

by Kiyoshi Kikuchi, Hisaaki Uchikado, Naoki Miura, Yoko Morimoto, Takashi Ito, Salunya Tancharoen, Kei Miyata, Rokudai Sakamoto, Chiemi Kikuchi, Narumi Iida, Naoto Shiomi, Terukazu Kuramoto, Naohisa Miyagi, Ko Ichi Kawahara
Published 2018

Beyond neurological disease: New targets for edaravone (Review)

by Kiyoshi Kikuchi, Hisaaki Uchikado, Naohisa Miyagi, Yoko Morimoto, Ito Takashi, Salunya Tancharoen, Naoki Miura, Kie Miyata, Rokudai Sakamoto, Chiemi Kikuchi, Narumi Iida, Naoto Shiomi, Terukazu Kuramoto, K. Ichi Kawahara
Published 2018

E8002 Reduces Adhesion Formation and Improves Joint Mobility in a Rat Model of Knee Arthrofibrosis

by Seiya Takada, Kentaro Setoyama, Kosuke Norimatsu, Shotaro Otsuka, Kazuki Nakanishi, Akira Tani, Tomomi Nakakogawa, Ryoma Matsuzaki, Teruki Matsuoka, Harutoshi Sakakima, Salunya Tancharoen, Ikuro Maruyama, Eiichiro Tanaka, Kiyoshi Kikuchi, Hisaaki Uchikado
Published 2022

Application of a novel anti-adhesive membrane, E8002, in a rat laminectomy model

by Kiyoshi Kikuchi, Kentaro Setoyama, Takuto Terashi, Megumi Sumizono, Salunya Tancharoen, Shotaro Otsuka, Seiya Takada, Kazuki Nakanishi, Koki Ueda, Harutoshi Sakakima, Ko Ichi Kawahara, Ikuro Maruyama, Gohsuke Hattori, Motohiro Morioka, Eiichiro Tanaka, Hisaaki Uchikado
Published 2019

Beyond free radical scavenging: Beneficial effects of edaravone (Radicut) in various diseases (Review)

by Kiyoshi Kikuchi, Nobuyuki Takeshige, Naoki Miura, Yoko Morimoto, Takashi Ito, Salunya Tancharoen, Kei Miyata, Chiemi Kikuchi, Narumi Iida, Hisaaki Uchikado, Naohisa Miyagi, Naoto Shiomi, Terukazu Kuramoto, Ikuro Maruyama, Motohiro Morioka, Ko Ichi Kawahara
Published 2018

Secondary prevention of stroke: Pleiotropic effects of optimal oral pharmacotherapy (review)

by Kiyoshi Kikuchi, Ko Ichi Kawahara, Naoki Miura, Takashi Ito, Yoko Morimoto, Salunya Tancharoen, Nobuyuki Takeshige, Hisaaki Uchikado, Rokudai Sakamoto, Naohisa Miyagi, Chiemi Kikuchi, Narumi Iida, Naoto Shiomi, Terukazu Kuramoto, Masaru Hirohata, Ikuro Maruyama, Motohiro Morioka, Eiichiro Tanaka
Published 2018

E8002 inhibits peripheral nerve adhesion by enhancing fibrinolysis of l-ascorbic acid in a rat sciatic nerve model

by Kiyoshi Kikuchi, Kentaro Setoyama, Seiya Takada, Shotaro Otsuka, Kazuki Nakanishi, Kosuke Norimatsu, Akira Tani, Harutoshi Sakakima, Ko Ichi Kawahara, Kazuya Hosokawa, Ryoji Kiyama, Megumi Sumizono, Salunya Tancharoen, Ikuro Maruyama, Gohsuke Hattori, Motohiro Morioka, Eiichiro Tanaka, Hisaaki Uchikado
Published 2020

Edaravone: A new therapeutic approach for the treatment of acute stroke

by Kiyoshi Kikuchi, Ko Ichi Kawahara, Naohisa Miyagi, Hisaaki Uchikado, Terukazu Kuramoto, Yoko Morimoto, Salunya Tancharoen, Naoki Miura, Kazunori Takenouchi, Yoko Oyama, Binita Shrestha, Fumiyo Matsuda, Yoshihiro Yoshida, Shinichiro Arimura, Kentaro Mera, Ko Ichi Tada, Narimasa Yoshinaga, Ryuichi Maenosono, Yoshiko Ohno, Teruto Hashiguchi, Ikuro Maruyama, Minoru Shigemori
Published 2018

Potential of edaravone for neuroprotection in neurologic diseases that do not involve cerebral infarction (Review)

by Kiyoshi Kikuchi, Ko Ichi Kawahara, Hisaaki Uchikado, Naohisa Miyagi, Terukazu Kuramoto, Tomoya Miyagi, Yoko Morimoto, Takashi Ito, Salunya Tancharoen, Naoki Miura, Kazunori Takenouchi, Yoko Oyama, Binita Shrestha, Fumiyo Matsuda, Yoshihiro Yoshida, Shinihiro Arimura, Kentaro Mera, Ko Ichi Tada, Narimasa Yoshinaga, Ryuichi Maenosono, Yoshiko Ohno, Teruto Hashiguchi, Ikuro Maruyama, Minoru Shigemori
Published 2018

Edaravone attenuates cerebral ischemic injury by suppressing aquaporin-4

by Kiyoshi Kikuchi, Salunya Tancharoen, Fumiyo Matsuda, Kamal Krishna Biswas, Takashi Ito, Yoko Morimoto, Yoko Oyama, Kazunori Takenouchi, Naoki Miura, Noboru Arimura, Yuko Nawa, Xiaojie Meng, Binita Shrestha, Shinichiro Arimura, Masahiro Iwata, Kentaro Mera, Hisayo Sameshima, Yoshiko Ohno, Ryuichi Maenosono, Yutaka Tajima, Hisaaki Uchikado, Terukazu Kuramoto, Kenji Nakayama, Minoru Shigemori, Yoshihiro Yoshida, Teruto Hashiguchi, Ikuro Maruyama, Ko ichi Kawahara
Published 2018

Minocycline attenuates both OGD-induced HMGB1 release and HMGB1-induced cell death in ischemic neuronal injury in PC12 cells

by Kiyoshi Kikuchi, Ko ichi Kawahara, Kamal Krishna Biswas, Takashi Ito, Salunya Tancharoen, Yoko Morimoto, Fumiyo Matsuda, Yoko Oyama, Kazunori Takenouchi, Naoki Miura, Noboru Arimura, Yuko Nawa, Xiaojie Meng, Binita Shrestha, Shinichiro Arimura, Masahiro Iwata, Kentaro Mera, Hisayo Sameshima, Yoshiko Ohno, Ryuichi Maenosono, Yoshihiro Yoshida, Yutaka Tajima, Hisaaki Uchikado, Terukazu Kuramoto, Kenji Nakayama, Minoru Shigemori, Teruto Hashiguchi, Ikuro Maruyama
Published 2018

HMGB1: A new marker for estimation of the postmortem interval

by Kiyoshi Kikuchi, Ko ichi Kawahara, Kamal Krishna Biswas, Takashi Ito, Salunya Tancharoen, Naoto Shiomi, Yoshiro Koda, Fumiyo Matsuda, Yoko Morimoto, Yoko Oyama, Kazunori Takenouchi, Naoki Miura, Noboru Arimura, Yuko Nawa, Shinichiro Arimura, Meng Xiao Jie, Binita Shrestha, Masahiro Iwata, Kentaro Mera, Hisayo Sameshima, Yoshiko Ohno, Ryuichi Maenosono, Yutaka Tajima, Hisaaki Uchikado, Terukazu Kuramoto, Kenji Nakayama, Minoru Shigemori, Yoshihiro Yoshida, Teruto Hashiguchi, Ikuro Maruyama
Published 2018