Preventive effects of Morus alba L. anthocyanins on diabetes in Zucker diabetic fatty rats

by Ariya Sarikaphuti, Thamthiwat Nararatwanchai, Teruto Hashiguchi, Takashi Ito, Sita Thaworanunta, Kiyoshi Kikuchi, Yoko Oyama, Ikuro Maruyama, Salunya Tancharoen
Published 2018

Taurine 7

by Nathan Back, Irun R. Cohen, Abel Lajtha N.S., John D. Lambris, Rodolfo Paoletti, Junichi Azuma, Stephen W. Schaffer, Takashi Ito
Published 2017

Potential of the angiotensin receptor blockers (ARBs) telmisartan, irbesartan, and candesartan for inhibiting the HMGB1/RAGE axis in prevention and acute treatment of stroke

by Kiyoshi Kikuchi, Salunya Tancharoen, Takashi Ito, Yoko Morimoto-Yamashita, Naoki Miura, Ko ichi Kawahara, Ikuro Maruyama, Yoshinaka Murai, Eiichiro Tanaka
Published 2018

Nucleophosmin may act as an alarmin: Implications for severe sepsis

by Yuko Nawa, Ko Ichi Kawahara, Salunya Tancharoen, Xiaojie Meng, Hisayo Sameshima, Takashi Ito, Yoshiki Masuda, Hitoshi Imaizumi, Teruto Hashiguchi, Ikuro Maruyama
Published 2018

Thrombomodulin exerts cytoprotective effect on low-dose UVB-irradiated HaCaT cells

by Masahiro Iwata, Ko ichi Kawahara, Hisashi Kawabata, Takashi Ito, Kentaro Mera, Kamal Krishna Biswas, Salunya Tancharoen, Yuko Higashi, Kiyoshi Kikuchi, Teruto Hashiguchi, Takuro Kanekura, Ikuro Maruyama
Published 2018

Cleavage of host cytokeratin-6 by lysine-specificgingipain induces gingival inflammation in periodontitis patients

by Salunya Tancharoen, Takashi Matsuyama, Ko Ichi Kawahara, Kenji Tanaka, Lyang Ja Lee, Miho Machigashira, Kazuyuki Noguchi, Takashi Ito, Takahisa Imamura, Jan Potempa, Kiyoshi Kikuchi, Ikuro Maruyama
Published 2018

HMGB1 as a therapeutic target in spinal cord injury: A hypothesis for novel therapy development (Review)

by Kiyoshi Kikuchi, Hisaaki Uchikado, Naoki Miura, Yoko Morimoto, Takashi Ito, Salunya Tancharoen, Kei Miyata, Rokudai Sakamoto, Chiemi Kikuchi, Narumi Iida, Naoto Shiomi, Terukazu Kuramoto, Naohisa Miyagi, Ko Ichi Kawahara
Published 2018

Induction of high mobility group box 1 release from serotonin-stimulated human umbilical vein endothelial cells

by Ko Ichi Kawahara, Teruto Hashiguchi, Kiyoshi Kikuchi, Salunya Tancharoen, Naoki Miura, Takashi Ito, Yoko Oyama, Yuko Nawa, Kamal K. Biswas, Xiaojie Meng, Yoko Morimoto, Binita Shrestha, Hisayo Sameshima, Ikuro Maruyama
Published 2018

Inhibition of HMGB1 by deep ocean water attenuates endotoxin-induced sepsis

by Ko ichi Kawahara, Teruto Hashiguchi, Takashi Ito, Kiyoshi Kikuchi, Yoko Morimoto, Toshiaki Shimizu, Yoko Oyama, Kazunori Takenouchi, Shin ichiro Arimura, Noboru Taniguchi, Ikuro Maruyama, Masahiro Iwata, Salunya Tancharoen, Masako Unoshima, Hideo Iwasaka
Published 2018

Beyond free radical scavenging: Beneficial effects of edaravone (Radicut) in various diseases (Review)

by Kiyoshi Kikuchi, Nobuyuki Takeshige, Naoki Miura, Yoko Morimoto, Takashi Ito, Salunya Tancharoen, Kei Miyata, Chiemi Kikuchi, Narumi Iida, Hisaaki Uchikado, Naohisa Miyagi, Naoto Shiomi, Terukazu Kuramoto, Ikuro Maruyama, Motohiro Morioka, Ko Ichi Kawahara
Published 2018

Secondary prevention of stroke: Pleiotropic effects of optimal oral pharmacotherapy (review)

by Kiyoshi Kikuchi, Ko Ichi Kawahara, Naoki Miura, Takashi Ito, Yoko Morimoto, Salunya Tancharoen, Nobuyuki Takeshige, Hisaaki Uchikado, Rokudai Sakamoto, Naohisa Miyagi, Chiemi Kikuchi, Narumi Iida, Naoto Shiomi, Terukazu Kuramoto, Masaru Hirohata, Ikuro Maruyama, Motohiro Morioka, Eiichiro Tanaka
Published 2018

Uric acid enhances alteplase-mediated thrombolysis as an antioxidant

by Kiyoshi Kikuchi, Kentaro Setoyama, Eiichiro Tanaka, Shotaro Otsuka, Takuto Terashi, Kazuki Nakanishi, Seiya Takada, Harutoshi Sakakima, Sumate Ampawong, Ko ichi Kawahara, Tomoka Nagasato, Kazuya Hosokawa, Yoichiro Harada, Mika Yamamoto, Chinatsu Kamikokuryo, Ryoji Kiyama, Motohiro Morioka, Takashi Ito, Ikuro Maruyama, Salunya Tancharoen
Published 2019

Mechanism of HMGB1 release inhibition from RAW264.7 cells by oleanolic acid in Prunus mume Sieb. et Zucc

by Ko Ichi Kawahara, Teruto Hashiguchi, Kazuo Masuda, Abbi R. Saniabadi, Kiyoshi Kikuchi, Salunya Tancharoen, Takashi Ito, Naoki Miura, Yoko Morimoto, Kamal K. Biswas, Yuko Nawa, Xiaojie Meng, Yoko Oyama, Kazunori Takenouchi, Binita Shrestha, Hisayo Sameshima, Toshiaki Shimizu, Taro Adachi, Masakazu Adachi, Ikuro Maruyama
Published 2018

The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells

by Kiyoshi Kikuchi, Ko Ichi Kawahara, Salunya Tancharoen, Fumiyo Matsuda, Yoko Morimoto, Takashi Ito, Kamal Krishna Biswas, Kazunori Takenouchi, Naoki Miura, Yoko Oyama, Yuko Nawa, Noboru Arimura, Masahiro Iwata, Yutaka Tajima, Terukazu Kuramoto, Kenji Nakayama, Minoru Shigemori, Yoshihiro Yoshida, Teruto Hashiguchi, Ikuro Maruyama
Published 2018

Edaravone, a synthetic free radical scavenger, enhances alteplase-mediated thrombolysis

by Kiyoshi Kikuchi, Kentaro Setoyama, Ko Ichi Kawahara, Tomoka Nagasato, Takuto Terashi, Koki Ueda, Kazuki Nakanishi, Shotaro Otsuka, Naoki Miura, Hisayo Sameshima, Kazuya Hosokawa, Yoichiro Harada, Binita Shrestha, Mika Yamamoto, Yoko Morimoto-Yamashita, Haruna Kikuchi, Ryoji Kiyama, Chinatsu Kamikokuryo, Salunya Tancharoen, Harutoshi Sakakima, Motohiro Morioka, Eiichiro Tanaka, Takashi Ito, Ikuro Maruyama
Published 2018

Potential of edaravone for neuroprotection in neurologic diseases that do not involve cerebral infarction (Review)

by Kiyoshi Kikuchi, Ko Ichi Kawahara, Hisaaki Uchikado, Naohisa Miyagi, Terukazu Kuramoto, Tomoya Miyagi, Yoko Morimoto, Takashi Ito, Salunya Tancharoen, Naoki Miura, Kazunori Takenouchi, Yoko Oyama, Binita Shrestha, Fumiyo Matsuda, Yoshihiro Yoshida, Shinihiro Arimura, Kentaro Mera, Ko Ichi Tada, Narimasa Yoshinaga, Ryuichi Maenosono, Yoshiko Ohno, Teruto Hashiguchi, Ikuro Maruyama, Minoru Shigemori
Published 2018

C-reactive protein induces high-mobility group box-1 protein release through activation of p38MAPK in macrophage RAW264.7 cells

by Ko ichi Kawahara, Kamal Krishna Biswas, Masako Unoshima, Takashi Ito, Kiyoshi Kikuchi, Yoko Morimoto, Masahiro Iwata, Salunya Tancharoen, Yoko Oyama, Kazunori Takenouchi, Yuko Nawa, Noboru Arimura, Meng Xiao Jie, Binita Shrestha, Naoki Miura, Toshiaki Shimizu, Kentaro Mera, Shin ichiro Arimura, Noboru Taniguchi, Hideo Iwasaka, Sonshin Takao, Teruto Hashiguchi, Ikuro Maruyama
Published 2018

Edaravone attenuates cerebral ischemic injury by suppressing aquaporin-4

by Kiyoshi Kikuchi, Salunya Tancharoen, Fumiyo Matsuda, Kamal Krishna Biswas, Takashi Ito, Yoko Morimoto, Yoko Oyama, Kazunori Takenouchi, Naoki Miura, Noboru Arimura, Yuko Nawa, Xiaojie Meng, Binita Shrestha, Shinichiro Arimura, Masahiro Iwata, Kentaro Mera, Hisayo Sameshima, Yoshiko Ohno, Ryuichi Maenosono, Yutaka Tajima, Hisaaki Uchikado, Terukazu Kuramoto, Kenji Nakayama, Minoru Shigemori, Yoshihiro Yoshida, Teruto Hashiguchi, Ikuro Maruyama, Ko ichi Kawahara
Published 2018

Minocycline attenuates both OGD-induced HMGB1 release and HMGB1-induced cell death in ischemic neuronal injury in PC12 cells

by Kiyoshi Kikuchi, Ko ichi Kawahara, Kamal Krishna Biswas, Takashi Ito, Salunya Tancharoen, Yoko Morimoto, Fumiyo Matsuda, Yoko Oyama, Kazunori Takenouchi, Naoki Miura, Noboru Arimura, Yuko Nawa, Xiaojie Meng, Binita Shrestha, Shinichiro Arimura, Masahiro Iwata, Kentaro Mera, Hisayo Sameshima, Yoshiko Ohno, Ryuichi Maenosono, Yoshihiro Yoshida, Yutaka Tajima, Hisaaki Uchikado, Terukazu Kuramoto, Kenji Nakayama, Minoru Shigemori, Teruto Hashiguchi, Ikuro Maruyama
Published 2018

HMGB1: A new marker for estimation of the postmortem interval

by Kiyoshi Kikuchi, Ko ichi Kawahara, Kamal Krishna Biswas, Takashi Ito, Salunya Tancharoen, Naoto Shiomi, Yoshiro Koda, Fumiyo Matsuda, Yoko Morimoto, Yoko Oyama, Kazunori Takenouchi, Naoki Miura, Noboru Arimura, Yuko Nawa, Shinichiro Arimura, Meng Xiao Jie, Binita Shrestha, Masahiro Iwata, Kentaro Mera, Hisayo Sameshima, Yoshiko Ohno, Ryuichi Maenosono, Yutaka Tajima, Hisaaki Uchikado, Terukazu Kuramoto, Kenji Nakayama, Minoru Shigemori, Yoshihiro Yoshida, Teruto Hashiguchi, Ikuro Maruyama
Published 2018